Results 131 to 140 of about 385,458 (304)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Analysis of seed yield components in oilseed Brassicas [PDF]

, 2008
Gajene vrste iz porodice Brassicaceae imaju veliki ekonomski značaj. U istraživanja su uključene dve sorte ozime uljane repice i dve sorte jare uljane repice (Brassica napus L.), dve sorte stočnog kelja (Brassica oleracea var. viridis) i dve sorte bele slačice (Sinapis alba L. subsp. alba syn. Brassica hirta). Ogled je postavljen u jesenjem i prolećnom
Marjanović-Jeromela, Ana, Marinković, Radovan, Jankulovska, Mirjana, Mikić, Aleksandar, Stojaković, Željka   +4 more
openaire  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Evaluation of Seed Yield and Related Components of Rapeseed Winter Cultivars Under Different Sowing dates in Karaj area [PDF]

Journal of Agricultural Science and Sustainable Production, 2010
Sowing date is the most important factor on yield and it's components of rapeseed. Suitable sowing dates make the environmental conditions during the days of emergence and seedling establishment favorable for plant. This experiment was conducted in split
D Roodi, H Amiri-Oghan, B Alizadeh
doaj  

A study of effects of low temperature stress on seed development and yield in wheat (Triticum aestivam L.) : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science in Seed Technology at Massey University [PDF]

, 1981
Temperature affects the growth, development, fertility and yield of cereals. The degree of sterility and subsequent yield reduction caused by extreme temperature stress depends upon the minimum level and duration of the stress temperature applied and the
Shrestha, Devaki
core  

Determining Relationships Between Seed Yield and Yield Components in Alfalfa

Pakistan Journal of Biological Sciences, 2006
Sengul, Meryem, Sengul, Süleyman
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

A Comparative Analysis of the Efficacy of Three Plant Growth Regulators and Dose Optimization for Improving Agronomic Traits and Seed Yield of Purple-Flowered Alfalfa (Medicago sativa L.)

Plants
This study evaluated the effects of different plant growth regulators and their concentration gradients on the agronomic traits, seed yield, and yield components of Medicago sativa L. cv. “Xinmu No. 5” alfalfa.
Xianwei Peng, Qunce Sun, Shuzhen Zhang, Youping An, Fengjun Peng, Jie Xiong, Ayixiwake Molidaxing, Shuming Chen, Yuxiang Wang, Bo Zhang   +9 more
doaj   +1 more source