Results 171 to 180 of about 820,864 (392)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Variance Component of Yield and Related Traits of Black Soybean Genotypes [PDF]
, 2012 The objective of this research was to determine the trait variance in black soybean lines in terms of yield and yield components. The materials used were F8 lines generated from hybridization of two local varieties, i.e.
Marwiyah, S. (Siti) +6 more
core
Genetic determinism of seed yield components in lucerne
, 2023 Seed production is a major component of the commercial development of a variety but breeding for seed yield is expensive. A set of 400 cultivated lucerne accessions were phenotyped for seed yield traits in two locations and genotyped with GBS markers. A large diversity was found among accessions but the heritability of the traits was moderate. QTL were
Julier, Bernadette +3 more
openaire +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Response of french bean (Phaseolus vulgaris L.) to rate and ratio of potassium fertilizer application [PDF]
, 1996 A field study was undertaken to evaluate the effect of potassium fertilizer, when applied in different ratios, as a basal or top dressing on vegetative growth, immature pod and seed yield of French bean as well as seed quality for planting purpose ...
U. R., Sangakkara
core
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Hybrid Varieties for Organic Cereals? Prospects and acceptance of hybrid breeding for organic production [PDF]
, 2006 Hybrid breeding utilizes the advantages characterizing F1 plants in a targeted manner: Vigour, uniformity, and a combination of all dominant traits of the parental lines.
Arncken, Christine, Dierauer, Hansueli
core
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Development of disease control strategies for organically grown field vegetables (DOVE) (OF0168) [PDF]
, 2002 This is the final report of Defra project OF0168 (DOVE). The attached main report starts with a more detailed and comprehensive Executive Summary, from which this text has been extracted.
Gladders, Dr Peter
core