Results 181 to 190 of about 820,864 (392)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Komponen Keragaman Sifat-sifat yang Berhubungan dengan Ketahanan terhadap Penggerek Polong (Etiella Inckenella Treitschke) pada Tanaman Kedelai (Glycine Max L. Merril) [PDF]

open access: yes, 2016
One of main problems in increasing soybean production is the attack of pests such as soybean pod borer (Etiella zinckenella Treitschke). The objectives of this research was to determine the variance components and heritability of various characters ...
Candra, A. (Agung)   +2 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Combining ability and heterosis for seed cotton yield, its components and quality traits inGossypium hirsutumL.

open access: hybrid, 2015
Madhuri Sawarkar   +3 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Seed yield components and seed yield of winter vetch species (Vicia spp.) depending on row spacing

open access: yesRatarstvo i Povrtarstvo, 2010
Ispitivan je uticaj međurednog razmaka (12,5 cm i 50 cm) na komponente prinosa i prinos semena maljave, panonske i ozime forme obične grahorice (V. villosa Roth, V. pannonica Crantz i V. sativa L.). Analizirani su broj biljaka po jedinici površine, broj grana po biljci, broj grana po jedinici površine, visina useva, dužina biljaka, indeks poleganja ...
Karagić, Đura   +6 more
openaire   +2 more sources

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