Results 61 to 70 of about 116,110 (259)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Supplemental light quality affects optimal seeding density of microgreens

Urban Agriculture & Regional Food Systems
Higher seeding densities can negatively affect the yield of microgreens. We quantified the effects of supplemental light quality and seeding density on the yield of microgreens. Seeds of red beet (Beta vulgaris L. ssp.
Isabela Scavacini deFreitas, Simone da Costa Mello, Krishna Nemali   +2 more
doaj   +1 more source

Enhancing rice yield by optimizing tillering through the transplantation of seedlings cultivated at a high density on crop straw boards

Journal of Integrative Agriculture
In the face of agricultural labor shortages, reducing labor and costs in rice production while meeting demand or increasing yield is crucial for sustainable agricultural development.
Yufei Ling, Qun Hu, Yuxin Xia, Kaiwei Zhang, Dihui Fu, Yuan Feng, Fangfu Xu, Guangyan Li, Zhipeng Xing, Hui Gao, Haiyan Wei, Hongcheng Zhang   +11 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Effects of different seedstrings on the nursery of Pyropia yezoensis

Journal of the World Aquaculture Society
Seedstring cultivation is a fundamental method for Pyropia yezoensis aquaculture, as it provides an artificial substrate for the attachment of P. yezoensis spores and growth of gametophytes. This method has been widely used in the P.
Qikun Xing, Jeong Hwa Hwang, Jae Woo Jung, Ji‐Sook Park, Charles Yarish, Norman Clough, Jin Suk Heo, Jang K. Kim   +7 more
doaj   +1 more source

Density Separation of Imbibed and Primed Vegetable Seeds

Journal of the American Society for Horticultural Science, 1989
Abstract The objective of this study was to determine the relationship between seed density and seed quality of vegetable seeds hydrated by imbibing or priming procedures. Species studied were: lettuce ( Lactuca sativa L.), tomato ( Lycopersicon ...
H. J. Hill, A. G. Taylor, T.-G. Min
openaire   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Seeding rates and seasons of cultivation on growth performance of cultivars of common bean

Semina: Ciências Agrárias, 2014
Seeding rates and seasons of cultivation on growth performance of cultivars of common bean While there are others aspects associated, such as climate, soil and crop management, the growth habit of the cultivar is one of the main factors involved in ...
Marcos Gleidson Pereira dos Santos , Abner José de Carvalho , Andréia Márcia Santos de Souza David , Hugo Tiago Ribeiro Amaro , Neiva Maria Batista Vieira , José Eustáquio de Souza Carneiro   +5 more
doaj   +1 more source