Results 91 to 100 of about 327,495 (306)

Detailed comparison of injection-seeded and self-seeded performance of a 1060nm gain-switched Fabry-Perot laser diode

, 2016
We investigate and compare the performance of a gain-switched picosecond Fabry-Perot laser diode operated at 1.06 µm under both injection- and self-seeded conditions.
Malinowski, A., Richardson, D.J., Roelens, M.A.F., Vu, K.T.   +3 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Cover Crop Planting Date x Seeding Rate Trial [PDF]

, 2013
When corn silage is harvested in the fall, the entire plant is removed, leaving the soil exposed through the winter. Many farmers have started to plant cover crops following corn harvest because of the multitude of benefits cover cropping brings to soil ...
Burke, Conner, Cummings, Erica, Darby, Heather, Harwood, Hannah, Monahan, Susan   +4 more
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Corn seeding rates and variable-rate seeding [PDF]

, 2007
The current demand for corn has generated a great deal of discussion this past winter of corn yields exceeding 300 bushels per acre. What management considerations should producers make when aiming for high yields?
Abendroth, Lori, Elmore, Roger W.
core   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Soybean Row Spacing and Seeding Rate

, 2018
Recommendations for soybean seeding rates have been targeted between 125,000 and 140,000 seeds/acre with the objective of targeting a final plant population of at least 100,000 plants/acre. It is understood a 15-in. row spacing has approximately 4.5 bushels/acre higher yields than 30-in. row spacing.
Tuttle, Terry, Licht, Mark
openaire   +5 more sources

Grain Yield and Nitrogen Use Efficiency of a Small‐Grain‐Weight Variety Grown Under Different Nitrogen and Seeding Rates in Direct‐Seeded Rice in South China

Food and Energy Security
Small‐grain‐weight rice varieties are popular in South China. However, to maintain grain yields comparable to medium‐grain‐weight varieties, adjustments in nitrogen (N) and seeding rate management may be necessary.
Xinyu Wang, Youqiang Fu, Qi Ruan, Xiangyu Hu, Junfeng Pan, Yanzhuo Liu, Rui Hu, Meijuan Li, Qunhuan Ye, Yuanhong Yin, Kaiming Liang, Xuhua Zhong   +11 more
doaj   +1 more source

Achievement of higher biomass, yield and quality of essential oil of Tagetes minuta L. through optimizing the sowing method and seeding rate. [PDF]

Front Plant Sci, 2023
Pal PK, Mahajan M, Thakur BK, Kapoor P, Shivani.   +4 more
europepmc   +1 more source