Results 101 to 110 of about 327,495 (306)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Construction of dominant rice population under dry cultivation by seeding rate and nitrogen rate interaction. [PDF]

open access: yesSci Rep, 2021
Jiang H   +13 more
europepmc   +1 more source

Sticky Seeding in Discrete-Time Reversible-Threshold Networks [PDF]

open access: yes, 2016
When nodes can repeatedly update their behavior (as in agent-based models from computational social science or repeated-game play settings) the problem of optimal network seeding becomes very complex.
Spencer, Gwen
core   +3 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Effect of Ultrasonic Ice Seeding on Cryopreservation of L-02 Hepatocyte

open access: yesZhileng xuebao, 2021
During the slow freezing process, the cell solution is super-cooled, which may cause uncontrollable intracellular ice formation. Ultrasonic ice seeding can reduce super-cooling and improve the cell survival rate.
Li Weijie   +3 more
doaj  

Winter Barley Seeding Rate, Cover Crop and Variety Trial [PDF]

open access: yes, 2017
With the revival of the small grains industry in the Northeast and the strength of the localvore movement, craft breweries and distilleries have expressed an interest in sourcing local barley for malting.
Cummings, Erica   +5 more
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Impact of peanut seeding rate on water-use efficiency and yield

open access: yesFrontiers in Agronomy
Seeds account for one of the highest costs in peanut production. Moreover, the climate in most of the Southeastern US is predicted to become drier and warmer throughout the growing season. Thus, this paper examines how seeding rates alter ecosystem water-
Gengsheng Zhang   +4 more
doaj   +1 more source

Winter Barley Seeding Rate, Cover Crop and Variety Trial [PDF]

open access: yes, 2016
With the revival of the small grains industry in the Northeast and the strength of the locavore movement, craft breweries and distilleries have expressed an interest in sourcing local barley for malting.
Cummings, Erica   +2 more
core   +1 more source

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