Results 131 to 140 of about 118,128,766 (281)

Ways of seeing trees: in memory John Berger

open access: yes
Opening with a quote from a John Berger poem, and unfolding to the soundtrack of a Hindustani raag bhairav, this short lyrical filmpoem alludes to Berger's famous early work of art criticism Ways of Seeing - and pays tribute to his work as writer, artist
Foyle, Naomi   +4 more
core   +3 more sources

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

View of Washington Valley From The Grounds of the Seeing Eye

open access: yes, 2008
This is the view from the 62 acre campus of the Seeing Eye located in Washington Valley Morris Township.
Beards, Daniel E.
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

To See or Not to See

open access: yesScientific American Mind, 2013
Michael C. Hout, Stephen D. Goldinger
  +5 more sources

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Threadbare. [PDF]

open access: yesBr J Gen Pract
Miller S.
europepmc   +1 more source

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