Results 151 to 160 of about 83,118,583 (348)

‘Seeing the clinic thrive has been amazing’ [PDF]

, 2017

openalex   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Impact of Prescription Drug Monitoring Program Implementation on Rates and Characteristics of People Seeing Multiple Prescribers in Primary Care: A Controlled Interrupted Time-Series Analysis. [PDF]

Med J Aust
Picco L, Jung M, Russell G, Lalic S, Fini MA, Lubman DI, Buchbinder R, Xia T, Nielsen S.   +8 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Correction: How Etuaptmumk/Two-Eyed Seeing is used in Indigenous health research: A scoping review. [PDF]

PLoS One
PLOS One Staff.
europepmc   +1 more source

Stoke Newington Literary Festival: John Berger: Ways of Seeing

, 2017
Talk by Andrea Luka Zimmerman on the collaboration with John Berger on her film Taskafa, Stories of the street. Born in Stoke Newington in 1926, John Berger was one of the most influential artists, critics and writers of his generation.
Zimmerman, Andrea Luka
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Data mining ‘problem youth’: Looking closer but not seeing better [PDF]

, 2016
Francisca Grommé
openalex  

Seeing the Other: the Depiction of China in British Documentary Films

, 2014
Gina Plana Espinet
openalex   +1 more source

Seeing the trees despite the forest: Applying recursive partitioning to the evaluation of drug treatment retention [PDF]

, 2008
Gerhard Hellemann, Bradley T. Conner, M. Douglas Anglin, Douglas Longshore   +3 more
openalex   +1 more source