Results 121 to 130 of about 158,243 (300)
Scientific Reports, 2017 To investigate the effects of age at diagnosis on metastatic breast cancer and patients’ prognosis, we collected patient data from the Surveillance, Epidemiology, and End Results (SEER) database.
Meng-Ting Chen +8 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
International Journal of General Medicine, 2021 Zi‘an Shao,1,2,* Shuai Zheng,3,* Chong Chen,3 Jun Lyu2 1The First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong Province, People’s Republic of China; 2Department of Clinical Research, The First Affiliated Hospital
Shao Z, Zheng S, Chen C, Lyu J
doaj
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Seven correlations between interpersonal violence and the progression of organised religion
HTS Teologiese Studies/Theological Studies, 2019 While the majority of organised religions determine the origins of religion itself in an act of divine revelation, social science literature takes an evolutionary perspective.
Marian G. Simion
doaj +1 more source
Forecasting age-related changes in breast cancer mortality among white and black US women: A functional approach [PDF]
The disparity in breast cancer mortality rates among white and black US women is widening with higher mortality rates among black women. We apply functional time series models on age-specific breast cancer mortality rates for each group of women, and ...
Farah Yasmeen +2 more
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The risk of contralateral breast cancer: a SEER-based analysis
British Journal of Cancer, 2021 V. Giannakeas, D. Lim, S. Narod
semanticscholar +1 more source
Study to describe characteristics of prediction models (published in 2023) developed using the SEER ...
Jie Ma +3 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source