Results 61 to 70 of about 109,939 (312)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Surgical Compliance and Survival Outcomes for Patients with Stage T1-2 Non-Small-Cell Lung Cancer
Cancer Management and Research, 2020 Siben Wang,1,* Weipu Mao,2,* Yi Wang,3,* Xiuquan Shi,4 Wei Wang,3 Lili Dai,3 Wenping Zhang1 1Department of Thoracic Surgery, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, Shanxi Province 046000, People’s Republic of China ...
Wang S +6 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Clinical and Experimental Obstetrics & GynecologyBackground: Ovarian yolk sac tumor (OYST) is a rare and malignant subtype of malignant ovarian germ cell tumors (MOGCT). Due to its rarity, few large-scale studies have systematically evaluated the prognostic factors for this tumor ...
Haiyan Chen, Dan Zhong, Dake Li
doaj +1 more source
To be SEER 1.0 or not to be SEER 2.0? That is one of a few questions
Online Brazilian Journal of Nursing, 2007 The intent of this editorial is to share the fears related to the migration to a new version of the OJS/PKP and to highlight the strengths of the OBJN with the use of the OJS. The editorial also poits out many questions related to the contribuition of the OBJN to the scholars as well as quastions that includ the critical issues of time, costs, and ...
openaire +2 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
International Journal of General Medicine, 2021 Yunxiao Liu, Hao Zhang, Mingyu Zheng, Chunlin Wang, Zhiqiao Hu, Yang Wang, Huan Xiong, BoYang Fan, Yuliuming Wang, Hanqing Hu, Qingchao Tang, Guiyu Wang Department of Colorectal Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin,
Liu Y +11 more
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