Results 81 to 90 of about 109,939 (312)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

SEER: Sustainable E-commerce with Environmental-impact Rating

, 2023
With online shopping gaining massive popularity over the past few years, this study identifies a promising opportunity for E-commerce platforms to tackle climate change and other environmental problems.
Caleb Wohn, Adiba Mahbub Proma, Karen Berger, Serena Uong, Katrina Smith Korfmacher, Ehsan Hoque, Md Saiful Islam, Varun Kumar   +7 more
core   +1 more source

Application of Machine Learning Techniques to Predict Bone Metastasis in Patients with Prostate Cancer

Cancer Management and Research, 2021
Wen-Cai Liu,1,2 Ming-Xuan Li,2 Wen-Xing Qian,3 Zhi-Wen Luo,1,4 Wei-Jie Liao,1,4 Zhi-Li Liu,1,4 Jia-Ming Liu1,4 1Department of Orthopaedic Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, People’s Republic of China; 2The ...
Liu WC, Li MX, Qian WX, Luo ZW, Liao WJ, Liu ZL, Liu JM   +6 more
doaj  

Informatics research using publicly available pathology data

Journal of Pathology Informatics, 2011
The day has not arrived when pathology departments freely distribute their collected anatomic and clinical data for research purposes. Nonetheless, several valuable public domain data sets are currently available, from the U.S. Government.
Jules J Berman
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

ModelMania (SEER)

Study to describe characteristics of prediction models (published in 2023) developed using the SEER ...
Jie Ma, Paula Dhiman, Biruk Tsegaye, Gary Collins   +3 more
core   +1 more source

Simple sensors used for measuring service times and counting pedestrians

, 2011
Bauer D, Ray M, Seer S. Simple sensors used for measuring service times and counting pedestrians. Transportation Research Record: Journal of the Transportation Research Board.
Stefan Seer, Ray, Markus, Markus Ray, Seer, Stefan, Bauer, Dietmar ; https://orcid.org/, Dietmar Bauer   +5 more
core   +1 more source

Construction and Validation of Two Novel Nomograms for Predicting the Overall Survival and Cancer-Specific Survival of NSCLC Patients with Bone Metastasis

International Journal of General Medicine, 2021
Qiu Dong,1 Jialin Deng,2 Tsz Ngai Mok,1 Junyuan Chen,1 Zhengang Zha1 1Center for Bone, Joint and Sports Medicine, The First Hospital of Jinan University, Jinan University, Guangzhou, Guangdong, People’s Republic of China; 2School of Medicine, Jinan ...
Dong Q, Deng J, Mok TN, Chen J, Zha Z
doaj  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Primary tumor size as a prognostic factor in duodenal neuroendocrine neoplasms ≤20 mm: a population-based SEER analysis

Endocrine Oncology
Objective: The prognostic value of primary tumor size in duodenal neuroendocrine neoplasms (dNENs) ≤20 mm remains uncertain. Although size is used to guide management, its independent effect on survival is unclear.
Giuseppe Lamberti, Francesco Panzuto, Maria Rinzivillo, Flaminia Benedetta Zoboli, Irene Zannini, Elisa Andrini, Elisabetta Dell’Unto, Riccardo Di Pangrazio, Davide Campana   +8 more
doaj   +1 more source