Results 61 to 70 of about 381,423 (286)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
La négation au service du leadership féminin : analyse du discous oral de quelques femmes leaders camerounaises [PDF]
The objective of this article is to describe and analyze the use of negation in the oral discourse (speech) of four Cameroonian woman leaders. Used as a reaction to the problem of water, road, and electricity, negation appears in the corpus analyzed ...
Jacques ZRA
doaj
Background/purpose: Recently, many reports have recommended surgical treatment for medication-related osteonecrosis of the jaw (MRONJ). However, MRONJ is more likely to occur in older patients with poor general condition and often necessitates extensive ...
Mitsunobu Otsuru +5 more
doaj +1 more source
Quantification of left ventricular longitudinal strain, strain rate, velocity and displacement in healthy horses by 2-dimensional speckle tracking [PDF]
Background: The quantification of equine left ventricular (LV) function is generally limited to short-axis M-mode measurements. However, LV deformation is 3-dimensional (3D) and consists of longitudinal shortening, circumferential shortening, and radial ...
De Clercq, Dominique +4 more
core +1 more source
One way to understand something is to break it up into parts. New research indicates that segmenting ongoing activity into meaningful events is a core component of perception and that this has consequences for memory and learning. Behavioral and neuroimaging data suggest that event segmentation is automatic and that people spontaneously segment ...
Jeffrey M, Zacks, Khena M, Swallow
openaire +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Clinical Classification of Mosaicism
The term ‘mosaic skin disorders’ encompasses conditions in which the skin is involved by mosaic mutations, including epidermal nevi, vascular nevi, connective tissue nevi and lipomatous nevi, among others.
Andrea Diociaiuti +3 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Segmental Spatiotemporal CNNs for Fine-grained Action Segmentation
Joint segmentation and classification of fine-grained actions is important for applications of human-robot interaction, video surveillance, and human skill evaluation. However, despite substantial recent progress in large-scale action classification, the
G Navarro +6 more
core +1 more source
A 59-year-old man presented for evaluation and excision of non-tender, fleshy nodules that were arranged in a dermatomal distribution from the left side of the chest to the left axilla. A biopsy specimen of a nodule was consistent with a neurofibroma. Owing to the lack of other cutaneous findings, the lack of a family history of neurofibromatosis, and ...
Adigun, Chris G, Stein, Jennifer
openaire +4 more sources

