Results 121 to 130 of about 1,383,033 (265)

Optimising and comparing source-extraction tools using objective segmentation quality criteria [PDF]

open access: green, 2021
Caroline Haigh   +6 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Enhanced Circuit Board Analysis: Infrared Image Segmentation Utilizing Markov Random Field (MRF) and Level Set Techniques

open access: yesEngineering Reports
Circuit board analysis plays a critical role in ensuring the reliability of electronic devices by identifying temperature distribution, assessing component health, and detecting potential defects.
T. Praveenkumar   +7 more
doaj   +1 more source

U-Net Convolutional Neural Network for Mapping Natural Vegetation and Forest Types from Landsat Imagery in Southeastern Australia

open access: yesJournal of Imaging
Accurate and comparable annual mapping is critical to understanding changing vegetation distribution and informing land use planning and management. A U-Net convolutional neural network (CNN) model was used to map natural vegetation and forest types ...
Tony Boston   +2 more
doaj   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

open access: yesAging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst   +4 more
wiley   +1 more source

The Associations Between Chronic Active Lesions and White Matter Disease: A 7 Tesla Imaging Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The relationship between paramagnetic rim lesions (PRLs) and surrounding normally appearing white matter (NAWM) disease, potentially contributory to the associations seen between PRLs and clinical impairment, is underexplored. Objectives To assess whether PRLs correlate with a greater degree of NAWM injury in early MS.
Ellie McCluey   +17 more
wiley   +1 more source

Fractional Lévy Stable Motion from a Segmentation Perspective

open access: yesFractal and Fractional
The segmentation analysis of the Golding–Cox mRNA dataset clarifies the description of these trajectories as a Fractional Lévy Stable Motion (FLSM). The FLSM method has several important advantages.
Aleksander A. Stanislavsky   +1 more
doaj   +1 more source

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