Results 61 to 70 of about 729,834 (302)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

SYNTACTIC EXPRESSIVENESS IN DESCRIBING THE AILMENTS OF YOUNG CHARACTERS IN THE NOVEL TURN OFF SPELLING BY EVA NEMESH’S

Sovremennye Issledovaniâ Socialʹnyh Problem, 2023
The relevance of the study is determined by several facts: firstly, in recent years, the interest of linguists in studying the expressiveness and emotionality of a child’s oral and written speech has enhanced; secondly, in modern teenage prose, which is ...
Elvina I. Akhmetzyanova, Elmira R. Ibragimova   +1 more
doaj   +1 more source

Disease stability in segmental and non-segmental vitiligo

Indian Dermatology Online Journal, 2022
Some therapeutic decisions in vitiligo depend on the likelihood of the disease remaining stable and inactive.To determine a period of disease stability in vitiligo following which reactivation was unlikely.This cross-sectional descriptive study was carried out in 200 patients where a detailed clinical history of the disease activity and stability over ...
Neha Taneja, V Sreenivas, Kanika Sahni, Vishal Gupta, M Ramam   +4 more
openaire   +4 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Vitamin D supplementation trials: Navigating the maze of unpredictable results

Perspectives in Clinical Research
Vitamin D supplementation studies in various pleiotropic outcomes often yield conflicting results. This complexity arises from various factors, including individual differences (baseline Vitamin D levels, genetics, ethnicity, age, and gender).
Shruti Singh, Rajesh Kumar Meena, Vikas Maharshi, Nishi Sinha, Neha Agarwal, Shuvasree Payra, Divya Harsha   +6 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Three‐dimensional body composition parameters using automatic volumetric segmentation allow accurate prediction of colorectal cancer outcomes

Journal of Cachexia, Sarcopenia and Muscle
Background Parameters obtained from two‐dimensional (2D) cross‐sectional images have been used to determine body composition. However, data from three‐dimensional (3D) volumetric body images reflect real body composition more accurately and may be better
Aiya Bimurzayeva, Min Jung Kim, Jong‐Sung Ahn, Ga Yoon Ku, Dokyoon Moon, Jinsun Choi, Hyo Jun Kim, Han‐Ki Lim, Rumi Shin, Ji Won Park, Seung‐Bum Ryoo, Kyu Joo Park, Han‐Jae Chung, Jong‐Min Kim, Sang Joon Park, Seung‐Yong Jeong   +15 more
doaj   +1 more source

Investigation of deep learning approaches for automated damage diagnostics in fiber metal laminates using Detectron2 and SAM

Frontiers in Artificial Intelligence
The impact damage is one of the major causes of structural failures in Fiber Metal Laminate (FML) plates, which are widely used in the aerospace and automotive industries due to their superior mechanical properties.
Sanjeev Kumar, Stefan Bosse, Chirag Shah
doaj   +1 more source

Subcellular object quantification with Squassh3C and SquasshAnalyst

BioTechniques, 2015
Quantitative image analysis plays an important role in contemporary biomedical research. Squassh is a method for automatic detection, segmentation, and quantification of subcellular structures and analysis of their colocalization.
Aurélien Rizk, Maysam Mansouri, Kurt Ballmer-Hofer, Philipp Berger   +3 more
doaj   +1 more source