Results 161 to 170 of about 39,077 (276)

A Plug‐and‐Play Volume Minimizing Micromixer

Advanced Science, EarlyView.
ABSTRACT Microscale fluid mixing has numerous applications where rapid and efficient mixing is required, including drug discovery, bio‐analysis and point‐of‐care diagnostics. Conventional soft lithography processes, however, make the integration of robust and reliable mixing difficult to implement in practice, especially across different flow rates ...
Kirill Kolesnik, Philipp Segeritz, Daniel J. Scott, David J. Collins   +3 more
wiley   +1 more source

Hyperspectral coherent anti-Stokes Raman scattering volumetric projection microscopy for assessing drug-cell interaction. [PDF]

Biomed Opt Express
Zhang C, Li Y, Yang Q, Fang Y, Zhang G, Zhou S, Hu R, Qu J, Liu L.   +8 more
europepmc   +1 more source

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

Advanced Science, EarlyView.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency, Tao Cui, Yimei Cai, Chloe Lok, Rachel E. Nokku, Ruoxian Huang, Grace L. Chu, Yumeng Xie, Saleem W. Abu‐Tayeh, Kaikai He, Chengjie Qiu, Junyi Wang, Paxton M. Paganelli, Ting Wang, Gabrielle Williams, Sreejith Nair, Huadong Pei, Dion K. Dickman, Stefano Vicini, Tingting Wang   +19 more
wiley   +1 more source

High-throughput multi-camera array microscope platform for automated 3D behavioral analysis of swimming zebrafish larvae. [PDF]

Commun Biol
Chen H, Li K, Kreiss L, Reamey P, Pierce LX, Zhang R, Da Luz R, Chaware A, Kim K, Cook CB, Yang X, Lerner JF, Doman J, Bègue A, Efromson J, Harfouche M, Horstmeyer G, McCarroll MN, Horstmeyer R.   +18 more
europepmc   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

Application of adaptive deep learning-based automatic segmentation in radiomics model for preoperative WHO/ISUP grading of clear cell renal cell carcinoma: a retrospective comparative study with manual segmentation. [PDF]

PeerJ
Zhu H, Chen Z, Zhang J, Yang M, Gu K, Bao W, Du Y, Hou S, Yao W.   +8 more
europepmc   +1 more source

Cellular Snowballing: Cell Adhesion and Migration Drive the Self‐Assembly of Cell‐Microgel Biohybrid Spheroids

Advanced Science, EarlyView.
A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie, Sina Kheirabadi, Changhao Li, Aneesh Risbud, Aswathy Sebastian, Istvan Albert, Sulin Zhang, Amir Sheikhi   +7 more
wiley   +1 more source

Proof of Concept of an Integrated Laser Irradiation and Thermal/Visible Imaging System for Optimized Photothermal Therapy in Skin Cancer. [PDF]

Sensors (Basel)
Novas D, Fortes A, Vieira P, Coelho JMP.
europepmc   +1 more source

ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

Advanced Science, EarlyView.
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao, Shannon Erhardt, Li Tang, Xiaotong Chen, Stephen M Farmer, Zixiu Cheng, Wen Chen, Ella Ziyuan Lu, Kihan Sung, Chang‐Ru Tsai, Mingjie Zheng, Sheng Zhang, Yang Liu, Jianxin Wang, Min Li, James F Martin, Jun Wang   +16 more
wiley   +1 more source

Real-time, high-resolution metabolic characterization of live bacteria using label-free optical metabolic imaging. [PDF]

NPJ Biofilms Microbiomes
Sorrells JE, Yang L, Iyer RR, Zaki FR, Markowicz AA, Monroy GL, Aksamitiene E, Marjanovic M, Boppart SA.   +8 more
europepmc   +1 more source