Results 171 to 180 of about 39,077 (276)

Single‐Cell Metabolic Imaging and Digital Scoring of Fat Tissue Remodeling by Label‐Free Metabolic Microscopy

Advanced Science, EarlyView.
Mid‐infrared optoacoustic microscopy (MiROM) acquires lipid‐ and protein‐ associated vibrational contrast in intact fat tissue without dyes, preserving native tissue architecture. Through lateral and axial segmentation, MiROM tracks intrinsic intracellular changes during postnatal remodeling. A quantitative spatial analysis tool (Q‐SAT) maps white‐ and
Myeongseop Kim, Constantin Berger, Alexander Wolf, Alina Peteranderl, Martin Klingenspor, Vasilis Ntziachristos, Yongguo Li, Miguel A. Pleitez   +7 more
wiley   +1 more source

Be⁺ assisted, simultaneous confinement of more than 15000 antihydrogen atoms. [PDF]

Nat Commun
Akbari R, de Araujo Azevedo LO, Baker CJ, Bertsche W, Bhatt NM, Bonomi G, Capra A, Carli I, Cesar CL, Charlton M, Cridland Mathad A, Del Vincio A, Duque Quiceno D, Eriksson SJ, Evans A, Ewins J, Fajans J, Friesen T, Fujiwara MC, Golino LM, Gomes Gonçalves MB, Hangst JS, Hayden ME, Hodgkinson D, Isaac CA, Jimenez AJU, Jones SA, Jonsell S, Madsen N, Marshall VR, McKenna JTK, Momose T, Nauta J, Oliveira AN, Peszka J, Powell A, Rasmussen CØ, Robertson-Brown T, Robicheaux F, Sacramento RL, Sarid E, Schoonwater J, Silveira DM, Singh J, Smith G, So C, Stracka S, Suh J, Swadling AG, Tharp TD, Thompson KA, Thompson RI, Thorpe-Woods E, Urioni M, van der Werf DP, Woosaree P, Wurtele JS.   +56 more
europepmc   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

Equity gaps in neglected tropical disease research in Malaysia: a systematic review, 2014-2024. [PDF]

BMC Public Health
Aminuddin MAH, Abdul Rahim FA, Naba A, Mohd Ngesom AM, Che Dom N.   +4 more
europepmc   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

Digital workflow for fabricating a patient-specific detachable 3D-printing model for mesiodens extraction to enhance surgical planning and dental education. [PDF]

BMC Oral Health
Shin YJ, Roske CB, Cho SH, Curtis J, Mai HN, Lee DH.   +5 more
europepmc   +1 more source

In Situ Characterisation of Hydrogels via Dynamic Interface Printing

Advanced Science, EarlyView.
ABSTRACT Hydrogels have become pivotal materials for tissue engineering, robotics, biomedical devices, and sensing applications due to their diverse material compositions and tunable mechanical properties. While significant effort has focused on developing novel manufacturing approaches such as extrusion bioprinting and light‐based fabrication methods,
Callum Vidler, Michael Halwes, David J. Collins   +2 more
wiley   +1 more source

Lightweight and precise cell classification based on holographic tomography-derived refractive index point cloud. [PDF]

J Biomed Opt
Wang H, Wu D, Zheng M, Zhang Z, Zhang W, Di J, Zhong L.   +6 more
europepmc   +1 more source

On the Origins of Toughness in Corymbia calophylla (Marri Tree) Nuts

Advanced Science, EarlyView.
We uncover the natural toughening mechanisms of the marri nut, including fiber pullout, crack deflection, and a viscoelastic matrix, which enable exceptional energy absorption and ductility comparable to Teflon, with an elastic modulus similar to acrylic.
Wegood M. Awad, Ahmed S. Dalaq, Marieh B. Al‐Handawi, Rezo Getsadze, Oraib Al‐Ketan, James Weston, Mohammed Daqaq, Panče Naumov   +7 more
wiley   +1 more source

Geometric and dosimetric evaluation of auto-segmentation of brain arteriovenous malformations using multimodal imaging in stereotactic radiosurgery. [PDF]

Front Neurosci
Di X, Xu W, Gong X, Sun M, Jin T, Xu Y, Zhu L, Zhu H, Mei G, Liu X.   +9 more
europepmc   +1 more source