Results 101 to 110 of about 23,265,687 (345)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Predictive air combat decision model with segmented reward allocation
Complex & Intelligent SystemsIn air combat missions, unmanned combat aerial vehicles (UCAVs) must take strategic actions to establish combat advantages, enabling effective tracking and attacking of enemy UCAVs. Currently, a lot of reinforcement learning algorithms are applied to the
Yundi Li +3 more
doaj +1 more source
Advances in Difference Equations, 2019 For the boundary value problem (BVP) of a second-order partial differential equation on a plane triangle area, we propose a new algorithm based on the Adomian decomposition method (ADM) combined with a segmented technique.
Yin-shan Yun +3 more
doaj +1 more source
Evaluation of a Novel Simulation Curriculum With the Segmented Model in Pediatric Cardiovascular Education. [PDF]
Front Public Health, 2022 Yang Y +4 more
europepmc +1 more source
A nonlinear variational method for signal segmentation and reconstruction using level set algorithm
, 2006 A nonlinear functional is considered in this letter for segmentation and noise removal of piecewise continuous signals containing binary information contaminated with Gaussian noise.
Mahmoodi, Sasan, Sharif, Bayan
core +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
A Speech-Level-Based Segmented Model to Decode the Dynamic Auditory Attention States in the Competing Speaker Scenes. [PDF]
Front Neurosci, 2021 Wang L, Wang Y, Liu Z, Wu EX, Chen F.
europepmc +1 more source
Time-Varying World Market Integration [PDF]
We propose a conditional measure of capital market integration that allows us to characterize both the cross-section and time-series of expected returns in developed and emerging markets.
Campbell R. Harvey, Geert Bekaert
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Interpretation of coefficients in segmented regression for interrupted time series analyses
BMC Medical Research MethodologyBackground Segmented regression, a common model for interrupted time series (ITS) analysis, primarily utilizes two equation parametrizations. Interpretations of coefficients vary between the two segmented regression parametrizations, leading to ...
Yongzhe Wang +5 more
doaj +1 more source