Results 81 to 90 of about 211,200 (266)

A segmented Adomian algorithm for the boundary value problem of a second-order partial differential equation on a plane triangle area

Advances in Difference Equations, 2019
For the boundary value problem (BVP) of a second-order partial differential equation on a plane triangle area, we propose a new algorithm based on the Adomian decomposition method (ADM) combined with a segmented technique.
Yin-shan Yun, Ying Wen, Temuer Chaolu, Randolph Rach   +3 more
doaj   +1 more source

Evaluation of a Novel Simulation Curriculum With the Segmented Model in Pediatric Cardiovascular Education. [PDF]

Front Public Health, 2022
Yang Y, Tang LF, Hua CZ, Mao JH, Hong YX.   +4 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Comparative safety of stent retriever designs for intracranial atherosclerotic disease related large vessel occlusion using agarose models

Scientific Reports
Establishing an optimal first-line approach for suspected intracranial atherosclerotic disease (ICAD)-related acute large vessel occlusion (LVO) remains challenging. We developed an ICAD model using an agarose phantom to investigate the specific features
Yukihiro Imaoka, Katsuhiro Mikami, Ai Fuchita, Satoshi Ikeda, Nice Ren, Shogo Watanabe, Soichiro Abe, Tomohide Yoshie, Satoshi Namitome, Syoji Kobashi, Hirotoshi Imamura, Koji Iihara   +11 more
doaj   +1 more source

A Speech-Level-Based Segmented Model to Decode the Dynamic Auditory Attention States in the Competing Speaker Scenes. [PDF]

Front Neurosci, 2021
Wang L, Wang Y, Liu Z, Wu EX, Chen F.
europepmc   +1 more source

ASPS: Augmented Segment Anything Model for Polyp Segmentation

Accepted by ...
Huiqian Li, Dingwen Zhang, Jieru Yao, Longfei Han, Zhongyu Li 0006, Junwei Han 0001   +5 more
openaire   +2 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Interpretation of coefficients in segmented regression for interrupted time series analyses

BMC Medical Research Methodology
Background Segmented regression, a common model for interrupted time series (ITS) analysis, primarily utilizes two equation parametrizations. Interpretations of coefficients vary between the two segmented regression parametrizations, leading to ...
Yongzhe Wang, Narissa J. Nonzee, Haonan Zhang, Kimlin T. Ashing, Gaole Song, Catherine M. Crespi   +5 more
doaj   +1 more source

Standardizing the Cardiac Radioablation Targeting Workflow: Enabling Semi-Automated Angulation and Segmentation of the Heart According to the American Heart Association Segmented Model. [PDF]

Adv Radiat Oncol, 2022
van der Ree MH, Visser J, Planken RN, Dieleman EMT, Boekholdt SM, Balgobind BV, Postema PG.   +6 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source