Results 81 to 90 of about 14,157,821 (311)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
A Generative Victim Model for Segmentation
CoRRWe find that the well-trained victim models (VMs), against which the attacks are generated, serve as fundamental prerequisites for adversarial attacks, i.e. a segmentation VM is needed to generate attacks for segmentation. In this context, the victim model is assumed to be robust to achieve effective adversarial perturbation generation.
Aixuan Li +4 more
openaire +5 more sources
Spectrally-Segmented-Incremental-PCA for Hyperspectral Image Classification
, 2022 Spectrally-Segmented-Incremental-PCA for Hyperspectral Image ...
MSH Shemul (15371017) +5 more
core
A Segmented Signal Progression Model for the Modern Streetcar System
Discrete Dynamics in Nature and Society, 2015 This paper is on the purpose of developing a segmented signal progression model for modern streetcar system. The new method is presented with the following features: (1) the control concept is based on the assumption of only one streetcar line operating ...
Baojie Wang +3 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Sequence Modeling via Segmentations
CoRR, 2017 recurrent neural networks, dynamic programming, structured ...
Chong Wang 0002 +5 more
openaire +3 more sources
Analyzing Temperature Effects on Mortality Within the R Environment: The Constrained Segmented Distributed Lag Parameterization [PDF]
Here we present and discuss the R package modTempEff including a set of functions aimed at modelling temperature effects on mortality with time series data.
Vito M. R. Muggeo
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Adverse Selection, Segmented Markets, and the Role of Monetary Policy [PDF]
A model is constructed in which trading partners are asymmetrically informed about future trading opportunities and where spatial and informational frictions limit arbitrage between markets.
Williamson, Stephen, Sanches, Daniel
core
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source