Results 101 to 110 of about 14,157,821 (311)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Predictive air combat decision model with segmented reward allocation

open access: yesComplex & Intelligent Systems
In air combat missions, unmanned combat aerial vehicles (UCAVs) must take strategic actions to establish combat advantages, enabling effective tracking and attacking of enemy UCAVs. Currently, a lot of reinforcement learning algorithms are applied to the
Yundi Li   +3 more
doaj   +1 more source

A segmented Adomian algorithm for the boundary value problem of a second-order partial differential equation on a plane triangle area

open access: yesAdvances in Difference Equations, 2019
For the boundary value problem (BVP) of a second-order partial differential equation on a plane triangle area, we propose a new algorithm based on the Adomian decomposition method (ADM) combined with a segmented technique.
Yin-shan Yun   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

ASPS: Augmented Segment Anything Model for Polyp Segmentation

open access: yes
Accepted by ...
Huiqian Li   +5 more
openaire   +3 more sources

Comparative safety of stent retriever designs for intracranial atherosclerotic disease related large vessel occlusion using agarose models

open access: yesScientific Reports
Establishing an optimal first-line approach for suspected intracranial atherosclerotic disease (ICAD)-related acute large vessel occlusion (LVO) remains challenging. We developed an ICAD model using an agarose phantom to investigate the specific features
Yukihiro Imaoka   +11 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Interpretation of coefficients in segmented regression for interrupted time series analyses

open access: yesBMC Medical Research Methodology
Background Segmented regression, a common model for interrupted time series (ITS) analysis, primarily utilizes two equation parametrizations. Interpretations of coefficients vary between the two segmented regression parametrizations, leading to ...
Yongzhe Wang   +5 more
doaj   +1 more source

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