Results 111 to 120 of about 23,265,687 (345)

Standardizing the Cardiac Radioablation Targeting Workflow: Enabling Semi-Automated Angulation and Segmentation of the Heart According to the American Heart Association Segmented Model. [PDF]

Adv Radiat Oncol, 2022
van der Ree MH, Visser J, Planken RN, Dieleman EMT, Boekholdt SM, Balgobind BV, Postema PG.   +6 more
europepmc   +1 more source

ROBAST: Development of a ROOT-Based Ray-Tracing Library for Cosmic-Ray Telescopes and its Applications in the Cherenkov Telescope Array

, 2015
We have developed a non-sequential ray-tracing simulation library, ROOT-based simulator for ray tracing (ROBAST), which is aimed to be widely used in optical simulations of cosmic-ray (CR) and gamma-ray telescopes.
Noda, Koji, Okumura, Akira, Rulten, Cameron   +2 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Scene Understanding Based on High-Order Potentials and Generative Adversarial Networks

Advances in Multimedia, 2018
Scene understanding is to predict a class label at each pixel of an image. In this study, we propose a semantic segmentation framework based on classic generative adversarial nets (GAN) to train a fully convolutional semantic segmentation model along ...
Xiaoli Zhao, Guozhong Wang, Jiaqi Zhang, Xiang Zhang   +3 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Study on the impact dynamics theoretical model of bidirectional limited single-layer vibration isolation system with segmented limit stiffness

Zhongguo Jianchuan Yanjiu
ObjectiveTo address the issue of nonlinear stiffness changes in isolation systems with limiters under impact excitation, an impact dynamics theoretical model and its anti-impact performance research are conducted.MethodsFirst, using the idea of segmented
Qian CHEN, Shaoyu XIAO, Guanjun ZHANG
doaj   +1 more source

Energy Deposition Studies for the Hi-Lumi LHC Inner Triplet Magnets

, 2015
A detailed model of the High Luminosity LHC inner triplet region with new large-aperture Nb3Sn magnets, field maps, corrector packages, and segmented tungsten inner absorbers was built and implemented into the FLUKA and MARS15 codes.
Cerutti, F., Esposito, L., Lechner, A., Mokhov, N. V., Rakhno, I. L., Striganov, S. I., Tropin, I. S.   +6 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Design and Development of Flow Fields with Multiple Inlets or Outlets in Vanadium Redox Flow Batteries

Batteries
In vanadium redox flow batteries, the flow field geometry plays a dramatic role on the distribution of the electrolyte and its design results from the trade-off between high battery performance and low pressure drops.
Marco Cecchetti, Mirko Messaggi, Andrea Casalegno, Matteo Zago   +3 more
doaj   +1 more source