Results 41 to 50 of about 2,425,653 (248)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Time Series Analysis of Cutaneous Leishmaniasis in Sabzevar Northeastern Iran Using Segmented Regression Model [PDF]

open access: yesInternational Journal of Epidemiologic Research, 2020
Background and aims: Cutaneous leishmaniasis (CL) is one of the most important parasitic diseases in the world. Sabzevar city is endemic area for CL in the north east of Iran.
Hadis Barati   +5 more
doaj   +1 more source

WI-Segmented-Water

open access: yes, 2019
Segmented water phase for image: WI-Filtered Segmentation performed using Watershed segmentation in Avizo.
Nathaly Lopes Archilha (5674033)   +4 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Oil-Segmented-Water

open access: yes, 2019
Segmented water phase for image: Oil-Filtered Segmentation performed using Watershed segmentation in Avizo.
Nathaly Lopes Archilha (5674033)   +4 more
core   +1 more source

Segmented flow meter data

open access: yes, 2021
This is the data for ``Segmented plasma flow meter response from kinetic simulations''
Guangdong Liu
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Nuclei segmentation via sparsity constrained convolutional regression [PDF]

open access: yes2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI), 2015
Automated profiling of nuclear architecture, in histology sections, can potentially help predict the clinical outcomes. However, the task is challenging as a result of nuclear pleomorphism and cellular states (e.g., cell fate, cell cycle), which are compounded by the batch effect (e.g., variations in fixation and staining). Present methods, for nuclear
Yin Zhou   +3 more
openaire   +2 more sources

Regression results of segmented indicators for the DIF_Useage.

open access: yes, 2023
Regression results of segmented indicators for the DIF_Useage.
Tao Cen (15242987)   +2 more
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

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