Results 231 to 240 of about 370,164 (308)

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Responsive Neurostimulation Therapy Outcomes in Two Small Bilateral Thalamic and Corticothalamic Subgroups of Patients with Drug-Resistant Epilepsy-A Single-Center Experience. [PDF]

NeuroSci
Krothapally R, Perven G, Veerapaneni D, Podkorytova I.   +3 more
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Development and temporal validation of a postoperative nomogram based on clinical, surgical, histopathological, and semi-quantitative EEG features for predicting seizure-free survival in children after focal epilepsy surgery. [PDF]

Front Pediatr
Dong X, Sun T.
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Precision therapeutics for early onset epilepsy: Allele-selective antisense oligonucleotides for SCN2A-related epilepsy. [PDF]

Mol Ther Nucleic Acids
Kim-McManus O.
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Clinical utility and tolerability of ketamine as adjunctive rescue therapy for refractory neonatal status epilepticus: a case report of a late preterm infant with multifocal hemorrhagic brain injury. [PDF]

Front Pediatr
Gulisano C, Pepe A, Amadori E, Caruggi S, Caratozzolo D, Nobili L, Striano P, Ramenghi LA, Calandrino A.   +8 more
europepmc   +1 more source

Elevated serum IL-18 and IL-37 levels and their association with seizure burden in paediatric epilepsy. [PDF]

Front Immunol
Zawadzka M, Gleń J, Waszak P, Pietruszka M, Lemska A, Trzeciak M, Mazurkiewicz-Bełdzińska M.   +6 more
europepmc   +1 more source

Enhancing the cognitive, psychological, and social outcomes of adults undergoing surgery for focal drug-resistant epilepsy: protocol for a scoping review. [PDF]

BMJ Neurol Open
Harvey EE, Coleman H, Bapat D, Brigiari G, Brigo F, Brown S, Carnegie SMD, Englot D, Fong MWK, Francis HM, Hogan I, Jetté N, Kanner A, McGonigal A, Mulligan BP, Oxenham DV, Perucca P, Wilson SJ.   +17 more
europepmc   +1 more source