Results 41 to 50 of about 191,939 (298)

Electrophoretic drug delivery for seizure control [PDF]

Science Advances, 2018
An implantable microfluidic ion pump prevents seizures in a mice by delivery of inhibitory neurotransmitters to the seizure source.
Proctor, Christopher M, Slézia, Andrea, Kaszas, Attila, Ghestem, Antoine, Del Agua, Isabel, Pappa, Anna-Maria, Bernard, Christophe, Williamson, Adam, Malliaras, George G   +8 more
openaire   +4 more sources

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Predictors of anti-convulsant treatment failure in children presenting with malaria and prolonged seizures in Kampala, Uganda. [PDF]

, 2009
BACKGROUND: In endemic areas, falciparum malaria remains the leading cause of seizures in children presenting to emergency departments. In addition, seizures in malaria have been shown to increase morbidity and mortality in these patients. The management
Staedke Sarah G, Rosenthal, Philip J, Sarah G Staedke, Staedke, Sarah G, Byarugaba Justus, Arthur Mpimbaza, Mpimbaza Arthur, Philip J Rosenthal, Justus Byarugaba, Ndeezi, Grace, Rosenthal Philip J, Mpimbaza, Arthur, Ndeezi Grace, Grace Ndeezi, Byarugaba, Justus   +14 more
core   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Joint modelling of event counts and survival times [PDF]

, 2009
We consider the analysis of data from the MRC Multicentre Trial for Early Epilepsy and Single Seizures (MESS), which was undertaken to assess the differences between two policies: immediate, or deferred treatment in patients with single seizures or ...
Rogers, Jennifer Kaye, Hemming, Karla, Hutton, Jane   +2 more
core  

Proceedings of the 2022 “Lifestyle Intervention for Epilepsy (LIFE)” symposium hosted by Cleveland Clinic

Epilepsia Open
Lifestyle interventions are strategies used to self‐manage medical conditions, such as epilepsy, and often complement traditional pharmacologic and surgical therapies.
Elizabeth Spurgeon, Robert Saper, Andreas Alexopoulos, Jane B. Allendorfer, Judith Bar, Jessica Caldwell, Mackenzie Cervenka, Sandra Darling, Stephen Dombrowski, Lisa Gallagher, Sara Lazar, Erik Modlo, Jim Perko, Martha Sajatovic, Bikat Tilahun, Nandan Yardi, Imad Najm   +16 more
doaj   +1 more source

Effects of Positive Airway Pressure Therapy on Seizure Control in Patients with Nocturnal Epilepsy and Obstructive Sleep Apnoea Syndrome

Türk Uyku Tıbbı Dergisi, 2020
Objective:Obstructive Sleep Apnoea syndrome (OSAS) is common in patients with epilepsy. A reduction in seizure frequency was reported following positive airway pressure (PAP) therapy.
Gülçin Benbir Şenel, Derya Karadeniz
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Comparison of short-term outcome between surgical and clinical treatment in temporal lobe epilepsy: A prospective study

, 2015
Objective: To compare the efficacy of medical and surgical treatment for refractory mesial temporal lobe epilepsy associated with hippocampal sclerosis (MTLE).
Costa, ALC, Guerreiro, MM, Yasuda, CL, Oliveira, ELP, Ribas, GC, Cardoso, TAMO, Montenegro, MA, Cendes, F, Tedeschi, H, Guerreiro, CAM, Li, LM   +10 more
core   +1 more source

Poor Seizure Control Among Children Attending a Tertiary Hospital in South Western Uganda – A Retrospective Study

International Journal of General Medicine, 2023
Jane Namusisi,1,2 Stella Kyoyagala,1 Josephine Nantongo,2 Mike Kyewalyanga,1,3 Stephen Sabiiti,1 Angelique Murorunkwere,1 Josephine Nambi Najjuma,1 Jane Nakibuuka,4 Mark Kaddumukasa,4 Martha Sajatovic,5 Peter Kalubi1 1Department of Pediatrics and Child ...
Namusisi J, Kyoyagala S, Nantongo J, Kyewalyanga M, Sabiiti S, Murorunkwere A, Najjuma JN, Nakibuuka J, Kaddumukasa M, Sajatovic M, Kalubi P   +10 more
doaj