Results 91 to 100 of about 63,498 (244)

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Propofol and Sevoflurane Anesthesia in Early Childhood Do Not Influence Seizure Threshold in Adult Rats. [PDF]

Int J Environ Res Public Health, 2021
Piwowarczyk P, Rypulak E, Sysiak-Sławecka J, Nieoczym D, Socała K, Wlaź A, Wlaź P, Turski W, Czuczwar M, Borys M.   +9 more
europepmc   +1 more source

Age‐Related Changes in Myeloid Cells and Their Impact on Subcutaneous Melanoma Growth in Mice

Aging and Cancer, EarlyView.
Our findings reveal that age‐related changes in subcutaneous melanoma growth and immunotherapy response are context‐dependent. In models where tumor growth and treatment resistance increase with age, this effect is partly driven by enhanced immunosuppression from myeloperoxidase‐active Gr‐1⁺ myeloid cells.
Kaitlyn M. Landreth, Dylan D. Thomas, Remi Nohoesu, Angisha Basnet, F. Heath Damron, Mary Garland‐Kledzik, Emel Sen Kilic, Tracy W. Liu   +7 more
wiley   +1 more source

4E-BP2-dependent translation in parvalbumin neurons controls epileptic seizure threshold. [PDF]

Proc Natl Acad Sci U S A, 2021
Sharma V, Sood R, Lou D, Hung TY, Lévesque M, Han Y, Levett JY, Wang P, Murthy S, Tansley S, Wang S, Siddiqui N, Tahmasebi S, Rosenblum K, Avoli M, Lacaille JC, Sonenberg N, Khoutorsky A.   +17 more
europepmc   +1 more source

The Associations Between Chronic Active Lesions and White Matter Disease: A 7 Tesla Imaging Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The relationship between paramagnetic rim lesions (PRLs) and surrounding normally appearing white matter (NAWM) disease, potentially contributory to the associations seen between PRLs and clinical impairment, is underexplored. Objectives To assess whether PRLs correlate with a greater degree of NAWM injury in early MS.
Ellie McCluey, Ahmad A. Toubasi, Jiacheng Wang, Habeeb F. Kazimuddin, Taegan Vinarsky, Caroline Gheen, Carynn Koch, Zachery Rohm, Bryan Hernandez, Margareta A. Clarke, Rachael Cheek, Rozita Khalili, Chaoyang Jin, Victoria Lim, John Kramer, Junzhong Xu, Ipek Oguz, Francesca Bagnato   +17 more
wiley   +1 more source

Central Dysmyelination in SSADH‐Deficient Humans and Mice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer, Henry H. C. Lee, Edward Yang, Cesar Alves, Mariarita Bertoldi, Caitlyn Fung, Spencer V. Steele, Eren Kule, Zijie Jin, Alexander Rotenberg, Jean‐Baptiste Roullet, Phillip L. Pearl   +11 more
wiley   +1 more source

Effect of the Extract of Aloe vera on the Pentylenetetrazol Induced Seizure in Male Mice

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2015
Background and Objectives: Epilepsy is the most common neurological disorder after stroke. Despite various anticonvulsants, researches continue to discover new drugs with better efficacy and less side-effects.
Nasrin Heidarieh, Maryam Najafifard, Maryam Khoshsokhan, Masomeh Najafifard, Maryam Niksokhan   +4 more
doaj  

Serial case report of high seizure threshold patients that responded to the lengthening of pulse width in ECT. [PDF]

Neuropsychopharmacol Rep, 2022
Katagai H, Yasui-Furukori N, Kawashima H, Suwa T, Tsushima C, Sato Y, Shimoda K, Tasaki H.   +7 more
europepmc   +1 more source

Serum Neurofilament Light Chain in Multiple Sclerosis: Superiority of Age‐ and BMI‐Corrected Z Scores/Percentiles Over Absolute Cutoff Values for Prediction of Treatment Response

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Prognostication of disease course and prediction of treatment response in multiple sclerosis is an unmet need. We compared the performance of serum neurofilament light chain Z scores (age‐ and BMI‐adjusted) with absolute concentrations for the prediction of response to disease‐modifying therapy.
Maximilian Einsiedler, Aleksandra Maleska Maceski, Sofia Sandgren, Johanna Oechtering, Sabine Schaedelin, Lisa Hofer, Amar Zadic, Juan Francisco Vilchez Gomez, Lester Melie‐Garcia, Alessandro Cagol, Riccardo Galbusera, Sebastian Finkener, Patrice Lalive, Marjolaine Uginet, Stefanie Müller, Caroline Pot, Amandine Mathias, Renaud Du Pasquier, Robert Hoepner, Andrew Chan, Giulio Disanto, Chiara Zecca, Marcus D’Souza, Lars G. Hemkens, Tobias Derfuss, Özgür Yaldizli, Patrick Roth, Claudio Gobbi, David Brassat, Björn Tackenberg, Henrik Zetterberg, Tjalf Ziemssen, Heinz Wiendl, Klaus Berger, Marco Hermesdorf, Fredrik Piehl, Ludwig Kappos, Cristina Granziera, Ahmed Abdelhak, David Leppert, Eline A. J. Willemse, Pascal Benkert, Jens Kuhle, Swiss Multiple Sclerosis Cohort Study (SMSC)   +43 more
wiley   +1 more source

Bilateral versus Unilateral Training With Rhythmic Auditory Cueing in Stroke Rehabilitation: Effects on Upper Limb Function and Interhemispheric Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Stroke is a leading cause of long‐term disability in adults, with upper limb hemiparesis being a common impairment. Traditional training is mostly aimed at paralyzed limbs, but the effect of bilateral training is still unclear.
Fangfang Qian, Yanhong Dai, Guoqiang Zheng, Qi Zhong, Jianliang Lu, Luying Hu, Youhua He, Zhuoming Chen   +7 more
wiley   +1 more source