Results 31 to 40 of about 1,591,675 (322)

The effect of cyclooxygenase-2 inhibition on pentylenetetrazole-induced seizure threshold in mice [PDF]

open access: yesFiyz̤, 2018
Background: Previous studies have shown the protective effect of cyclooxygenase (COX) enzyme in development of convulsions. However, involvement of COX-2 in the pathogenesis of epilepsy is not yet well-known. The present study was designed to investigate
Azam Mesdaghinia   +2 more
doaj   +2 more sources

The effects of intra-cerebroventricular administered rocuronium on the central nervous system of rats and determination of its epileptic seizure-inducing dose

open access: yesRevista Brasileira de Anestesiologia, 2017
Background: The aim of this study was to investigate the effects of intracerebroventricularly administered rocuronium bromide on the central nervous system, determine the seizure threshold dose of rocuronium bromide in rats, and investigate the effects ...
Mehmet Baykal   +7 more
doaj   +3 more sources

The Contribution of Normal Pregnancy to Eclampsia. [PDF]

open access: yesPLoS ONE, 2015
Eclampsia, clinically defined as unexplained seizure in a woman with preeclampsia, is a life threatening complication unique to the pregnant state. However, a subpopulation of women with seemingly uncomplicated pregnancies experience de novo seizure ...
Abbie Chapman Johnson   +3 more
doaj   +1 more source

Anticonvulsant Profile of Selected Medium-Chain Fatty Acids (MCFAs) Co-Administered with Metformin in Mice in Acute and Chronic Treatment

open access: yesMolecules, 2023
In contrast to the other components of the medium-chain triglycerides ketogenic diet (MCT KD), i.e., caprylic acid (CA8), a comprehensive evaluation of caproic (CA6) and lauric acids’ (CA12) properties in standard chemical and electrical seizure tests in
Mateusz Pieróg   +5 more
doaj   +1 more source

Magnesium sulfate treatment reverses seizure susceptibility and decreases neuroinflammation in a rat model of severe preeclampsia. [PDF]

open access: yesPLoS ONE, 2014
Eclampsia, defined as unexplained seizure in a woman with preeclampsia, is a life-threatening complication of pregnancy with unclear etiology. Magnesium sulfate (MgSO4) is the leading eclamptic seizure prophylactic, yet its mechanism of action remains ...
Abbie Chapman Johnson   +6 more
doaj   +1 more source

The ictal EEG in ECT: A systematic review of the relationships between ictal features, ECT technique, seizure threshold and outcomes

open access: yesBrain Stimulation, 2020
Objective: To provide guidance for ECT practitioners in utilising the ictal EEG to inform treatment decisions. Methods: A systematic review of studies examining the ictal EEG, treatment technique, seizure threshold and treatment outcomes was conducted ...
Rohan Francis-Taylor   +3 more
doaj   +1 more source

Effect of different agonistic experiences on behavioural seizures in fully amygdala kindled rats [PDF]

open access: yes, 1992
Fully amygdala kindled rats were exposed to two different inter-male agonistic experiences in order to study the interaction between epilepsy and acute social stress.
Beldhuis, Hans J.A.,   +2 more
core   +13 more sources

Connexin36 knockout mice display increased sensitivity to pentylenetetrazol-induced seizure-like behaviors [PDF]

open access: yes, 2010
Large-scale synchronous firing of neurons during seizures is modulated by electrotonic coupling between neurons via gap junctions. To explore roles for connexin36 (Cx36) gap junctions in seizures, we examined the seizure threshold of connexin36 knockout (
Cursons, Raymond T.   +7 more
core   +2 more sources

Seizure threshold, hormones and anti epileptic drugs

open access: yesUniversa Medicina, 2008
The concept of seizure threshold holds that everyone has a certain balance between excitatory and inhibitory forces in the brain. A low seizure threshold makes it easier for epilepsy to develop and easier for someone to elicit single seizure.
Harsono Harsono
doaj   +1 more source

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