Results 41 to 50 of about 1,591,675 (322)
Effects of physiological parameter evolution on the dynamics of tonic-clonic seizures.
The temporal and spectral characteristics of tonic-clonic seizures are investigated using a neural field model of the corticothalamic system in the presence of a temporally varying connection strength between the cerebral cortex and thalamus.
F Deeba, P Sanz-Leon, P A Robinson
doaj +1 more source
Background and Aims: Electroconvulsive therapy (ECT) is the most effective treatment modality for severe and medication-resistant psychiatric disorders. ECT provokes generalized tonic-clonic seizures.
Chhaya P Joshi +5 more
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Hippocampal Melatonin Receptors Modulate Seizure Threshold [PDF]
Summary: Purpose: The pineal hormone melatonin has been shown to enhance hippocampal excitability. We therefore investigated whether inactivation of hippocampal melatonin receptors affects behavioral seizures. Methods: Intrahippocampal infusions were performed in rats to study the effect of different melatonin receptor antagonists on behavioral ...
Lee S, Stewart, L Stan, Leung
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Functional MRI during hippocampal deep brain stimulation in the healthy rat brain [PDF]
Deep Brain Stimulation (DBS) is a promising treatment for neurological and psychiatric disorders. The mechanism of action and the effects of electrical fields administered to the brain by means of an electrode remain to be elucidated.
Boon, Paul +9 more
core +3 more sources
Structural imaging biomarkers of sudden unexpected death in epilepsy. [PDF]
Sudden unexpected death in epilepsy is a major cause of premature death in people with epilepsy. We aimed to assess whether structural changes potentially attributable to sudden death pathogenesis were present on magnetic resonance imaging in people who ...
Balestrini, Simona +12 more
core +3 more sources
Lowered seizure threshold on olanzapine [PDF]
Olanzapine has been licensed in the UK since 1996 for schizophrenia. Along with other atypical antipsychotics it is being used increasingly, with roughly equivalent therapeutic effect but better side-effect profiles than more traditional antipsychotics ([Lader, 1999][1]).
Woolley, J, Smith, S
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Modeling glial contributions to seizures and epileptogenesis: cation-chloride cotransporters in Drosophila melanogaster. [PDF]
Flies carrying a kcc loss-of-function mutation are more seizure-susceptible than wild-type flies. The kcc gene is the highly conserved Drosophila melanogaster ortholog of K+/Cl- cotransporter genes thought to be expressed in all animal cell types.
Zeid M Rusan +2 more
doaj +1 more source
Inhomogeneous cortical synchronization and partial epileptic seizures [PDF]
Objective: Interictal synchronization clusters have recently been described in several publications using diverse techniques, including neurophysiological recordings and fMRI, in patients suffering from epilepsy.
García de Sola, Rafael +3 more
core +1 more source
PUFAs, A Dietary Supplement and Seizure Threshold
Investigators at the University of Toronto, Canada studied the effects of chronic dietary supplementation with omega-3 polyunsaturated fatty acids (PUFAs) derived from fish oil on seizure thresholds in the amygdala as well as on blood and brain PUFA ...
J Gordon Millichap
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Introduction: A high seizure threshold (ST) is an impeding factor in certain patients, potentially preventing a successful electroconvulsive therapy (ECT) treatment. Several pharmacological and non-pharmacological methods have been put forward to augment
J. Buday +9 more
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