Results 81 to 90 of about 1,591,675 (322)

Ripple oscillations in the left temporal neocortex are associated with impaired verbal episodic memory encoding

open access: yes, 2018
Background: We sought to determine if ripple oscillations (80-120Hz), detected in intracranial EEG (iEEG) recordings of epilepsy patients, correlate with an enhancement or disruption of verbal episodic memory encoding.
Berry, Brent   +26 more
core   +1 more source

Understanding Epileptiform After-Discharges as Rhythmic Oscillatory Transients [PDF]

open access: yes, 2017
Electro-cortical activity in patients with epilepsy may show abnormal rhythmic transients in response to stimulation. Even when using the same stimulation parameters in the same patient, wide variability in the duration of transient response has been ...
Baier, Gerold   +2 more
core   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

A Hidden Markov Factor Analysis Framework for Seizure Detection in Epilepsy Patients [PDF]

open access: yes, 2019
Approximately 1% of the world population suffers from epilepsy. Continuous long-term electroencephalographic (EEG) monitoring is the gold-standard for recording epileptic seizures and assisting in the diagnosis and treatment of patients with epilepsy ...
Madadi, Mahboubeh
core   +2 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Efficacy of low and high frequency Deep Brain Stimulation in epilepsy [PDF]

open access: yes, 2008
Purpose: Deep brain stimulation using a neurocybernetic device and intracranially implanted electrodes is currently being investigated as a treatment for refractory epilepsy.
Boon, Paul, Wyckhuys, Tine
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Critical Evaluation of P2X7 Receptor Antagonists in Selected Seizure Models. [PDF]

open access: yesPLoS ONE, 2016
The ATP-gated P2X7 receptor (P2X7R) is a non-selective cation channel which senses high extracellular ATP concentrations and has been suggested as a target for the treatment of neuroinflammation and neurodegenerative diseases.
Wolfgang Fischer   +8 more
doaj   +1 more source

The effect of sertraline and 8-OH-DPAT on the PTZinduced seizure threshold: Role of the nitrergic system [PDF]

open access: yes, 2017
Purpose Serotonin is a key regulatory neurotransmitter in the CNS which plays an important role in seizure through different receptors, especially the 5HT1A subtype.
Davoudi, S., Heydari, A.
core   +1 more source

Home - About - Disclaimer - Privacy