Results 211 to 220 of about 333,130 (317)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

New-Onset Complex Partial Seizures Progressing to Intractable Epilepsy in a Young Female With Bifrontal Encephalomalacia and a Remote History of Traumatic Brain Injury. [PDF]

Clin Case Rep
Villegas KJ, Sorathia A, Salib M, Escobar J, Conroy N.   +4 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Study of Clinico-Etiological Profile of New-Onset Seizure in Infants.

J Pharm Bioallied Sci
Shanmugapriya N, Goyal P, Mehta N.
europepmc   +1 more source

Duration of EEG monitoring needed to ensure a low risk of seizure recurrence in hospitalized patients. [PDF]

J Neurol
Krishnamurthy PV, Philibert-Rosas S, Rivkin M, Brace CJ, Haworth SE, Fatima S, Selte A, Kalkach Aparicio M, Struck AF.   +8 more
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Neurologist's Black Swan: Molecular Basis of Prenatal Seizures. [PDF]

Int J Mol Sci
Kustova AO, Medyanik AD, Anisimova PE, Tarabykin VS, Kondakova EV.   +4 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

From Seconds to Seasons: First-in-Human Insights from a Chronic Subscalp EEG System. [PDF]

Epilepsy Curr
Agashe S.
europepmc   +1 more source

Epileptic Seizures Related to Cerebral Venous Sinus Thrombosis: Clinicoradiological Findings and Cases of Delayed Diagnosis.

, 2014
Nergiz Hüseyinoğlu, Hatice Köse Özlece, Ürfettin Hüseyınoğlu, Metin Ekinci, Ataman Serim   +4 more
openalex   +1 more source