Results 111 to 120 of about 13,025,930 (315)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Full Slime Cyanidation Leaching of the Primary Gold Ore from a Metallurgical Processing Plant in Gansu

open access: yesKuangchan zonghe liyong
This is an article in the field of metallurgical engineering. A beneficiation and smelting plant processes two kinds of gold ores: primary ore and oxidized ore. The primary ore is treated by conventional flotation process.
Yanbo CHEN   +3 more
doaj   +1 more source

INFLUENCE OF DIFFERENT VINE ROOTSTOCKS ON THE VOLATILE COMPOSITION OF RED WINES FROM KAYLASHKI RUBIN GRAPEVINE VARIETY

open access: yesScientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2021
In order to determine the effect of some rootstocks on the volatile composition of red wines from three harvests (2017, 2018 and 2019) of the grafted interspecific hybrid variety Kaylashki Rubin a gas chromatographic (GC-FID) study was performed.
DIMITAR R. DIMITROV, ANATOLI M. ILIEV
doaj  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Protein and starch content in winter wheat grain at different stages of growth and maturation

open access: yesЗерновое хозяйство России
The current study was conducted in 2018, 2019 and 2021, on the experimental plots of the Volga Region RIBSP. The object of the study was the winter common wheat variety ‘Povolzhskaya Niva’.
I. I. Sharapov   +2 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Flotation of an Arsenic Bearing High Sulfur Gold Mine in Gansu Province

open access: yesKuangchan zonghe liyong
This is an article in the field of mineral processing engineering. The gold mineral in an arsenic bearing high sulfur gold mine has a close symbiotic relationship with pyrite and arsenopyrite, and the recovery rate of concentrate gold is not ideal in the
Yanbo CHEN   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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