Results 251 to 260 of about 13,377,413 (367)

Mixed-Weight Committee Selection in Proof-of-Stake: Tunable Stake-Baseline Mixing with Exponential Tail Guarantees and Incentive Compatibility [PDF]

I. R. Solomka, B. B. Liubinskyi, B. O. Peniak   +2 more
openalex   +1 more source

Resource selection by animals: statistical design and analysis for field studies.

, 1994
B. Manly, L. McDonald, Dana L. Thomas
semanticscholar   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Comparison Study of Different Feature Selection Techniques for the Diagnosis of Alzheimer's Disease. [PDF]

Am J Alzheimers Dis Other Demen
Masood F, Al-Hyari A, Al-Wajidi W, Alzheimer’s Disease Neuroimaging Initiative.   +3 more
europepmc   +1 more source

CRISPR genome editing using a combined positive and negative selection system

Ishrya Sharma, Kelly Hall, Shannon Moonah   +2 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

A selection index with minimal genetic relatedness for multi-trait data via binary quadratic programming. [PDF]

Plant Methods
Montesinos-López OA, Montesinos-López A, Hernández-Suárez CM, Alemu A.   +3 more
europepmc   +1 more source

Monitoring of building carbon footprint at different construction stages depending on building materials selection [PDF]

Vadim Sviridenko
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Sexual Dimorphism in Three Populations of the Chiala Mountain Salamander, Batrachuperus karlschmidti (Caudata: Hynobiidae). [PDF]

Animals (Basel)
Liu X, Shen C, Xu Y, Song J, Lou M, Xiong J.   +5 more
europepmc   +1 more source