Results 81 to 90 of about 10,138,963 (347)
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
wiley +1 more source
Land Cover Site Selection [PDF]
The purpose of the resource is to determine the major land cover type at a Land Cover Sample Site.
The GLOBE Program, University Corporation for Atmospheric Research (UCAR)
core
Comparing and Combining Lexicase Selection and Novelty Search
Lexicase selection and novelty search, two parent selection methods used in evolutionary computation, emphasize exploring widely in the search space more than traditional methods such as tournament selection. However, lexicase selection is not explicitly
Forstenlechner Stefan+7 more
core +1 more source
ENGINEERING DESIGN: EICOSANE MICROCAPSULES SYNTHESIS AND APPLICATION IN POLYURETHANE FOAMS AIMING TO DIMINISH WHEELCHAIR CUSHION EFFECT ON SKIN TEMPERATURE [PDF]
Thermal comfort of wheelchairs still requires improvements, since users remain on the chair for as long as 12 h a day. Increased sweating makes the skin more susceptible to colonization by fungi and bacteria, and may cause pressure ulcers. In this sense,
ELISA M. BERETTA+4 more
doaj
Objectives. Developing reliable and accurate analytical methods is necessary for comparative pharmaceutical analysis using physicochemical, biological (in vitro), preclinical, and clinical trials.
D. I. Zybin+6 more
doaj +1 more source
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source
High-dimensional variable selection
This paper explores the following question: what kind of statistical guarantees can be given when doing variable selection in high-dimensional models? In particular, we look at the error rates and power of some multi-stage regression methods.
Roeder, Kathryn, Wasserman, Larry
core +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
Population Improvement Through Recurrent Selection in Rice. Prospect for Maker Assisted Recurrent Selection and Genome-Wide Selection. W011 [PDF]
Since 1992, we have been carrying out an upland rice breeding program for Latin American and the Caribbean based on the improvement of synthetic populations of broad genetic diversity through recurrent selection (RS).
Ahmadi, Nourollah+8 more
core
Natural selection as coarsening
Analogies between evolutionary dynamics and statistical mechanics, such as Fisher's second-law-like "fundamental theorem of natural selection" and Wright's "fitness landscapes", have had a deep and fruitful influence on the development of evolutionary ...
Smerlak, Matteo
core +1 more source