Results 111 to 120 of about 4,222,943 (302)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Effects of Biases in Geometric and Physics-Based Imaging Attributes on Classification Performance

open access: yesJournal of Imaging
Learned systems in the domain of visual recognition and cognition impress in part because even though they are trained with datasets many orders of magnitude smaller than the full population of possible images, they exhibit sufficient generalization to ...
Bahman Rouhani, John K. Tsotsos
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Other title: Title from HTML header (viewed Nov. 9, 2011): Judicial Selection Commission

open access: yes, 2015
Updated irregularly; Began in 2002?; Title from main search screen (publisher's Web site, viewed Nov. 9, 2011).; At head of title: State of Connecticut.; Harvested from the web on 4/18/15Official website of the Connecticut Judicial Selection Commission ...

core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

EL EXPERIMENTO NATURAL COMO UN NUEVO DISEÑO CUASI-EXPERIMENTAL EN INVESTIGACIÓN SOCIAL Y DE SALUD NATURAL EXPERIMENT AS A NEW QUASI-XPERIMENTAL DESIGN IN SOCIAL AND HEALTH-RELATED SCIENCES

open access: yesCiencia y Enfermería, 2008
En las ciencias sociales y de la salud actualmente comienza a ser conocido un diseño denominado como "experimento natural", que se caracteriza por ser un tipo de cuasi-experimento en que la asignación de tratamiento no es hecha por el investigador sino ...
LILIAN NASS KUNSTMANN   +1 more
doaj  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Estimating treatment effectiveness with sample selection [PDF]

open access: yes
We consider a situation where treatment outcome is observed after two stages of selection; first of participation into the treatment, then in completion of the treatment. Estimates were obtained using two methods.
Vidhura Tennekoon   +3 more
core  

Selection Bias [PDF]

open access: yesNeuroepidemiology, 2009
Timothy L. Lash   +2 more
  +4 more sources

Home - About - Disclaimer - Privacy