Results 81 to 90 of about 1,049,088 (304)
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Sensing population distribution from satellite imagery via deep learning: model selection, neighboring effect, and systematic biases [PDF]
Xiao Huang +5 more
openalex +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
An Empirical Analysis of the Effects of Selectivity and Endogeneity Problems on Returns to Education [PDF]
This articles aims at evaluating the effects of selectivity and endogeneity problems on returns to education caused by individuals' decision to attend school and to participate in the labour market.
Abolghasem Naderi
doaj
Assessment of publication bias, selection bias, and unavailable data in meta-analyses using individual participant data: a database survey [PDF]
Ikhlaaq Ahmed +2 more
openalex +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Tumor size and postoperative kidney function following radical nephrectomy
Robert J Ellis,1–4 Victoria M White,5,6 Damien M Bolton,7,8 Michael D Coory,8 Ian D Davis,9,10 Ross S Francis,2–4 Graham G Giles,5,8 Glenda C Gobe,3,4 Rachel E Neale,1 Simon T Wood,3–4,10 Susan J Jordan1,31Department of Population ...
Ellis RJ +10 more
doaj
Shift work and cardiovascular disease – do the new studies add to our knowledge?
The association of shift work with cardiovascular disease (CVD) has been studied for decades with new systematic reviews repeatedly being published (1–4). Based on 34 studies and over 2 million employees, the systematic review of Vyas et al (4) concluded
Mikko Härmä +2 more
doaj +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source

