Assessment of publication bias, selection bias, and unavailable data in meta-analyses using individual participant data: a database survey [PDF]
Ikhlaaq Ahmed +2 more
openalex +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Pseudo-Panel Decomposition of the Blinder–Oaxaca Gender Wage Gap
This article introduces a novel approach to decomposing the Blinder–Oaxaca gender wage gap using pseudo-panel data. In many developing countries, panel data are not available; however, understanding the evolution of the gender wage gap over time requires
Jhon James Mora, Diana Yaneth Herrera
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Relative age effects in Rugby union and Rugby league: a systematic review and meta-analysis
IntroductionRelative Age Effects (RAEs) are prominent factors affecting youth sport participation and talent identification and selection processes. In rugby, RAEs appear to be prevalent in both Rugby League (RL) and Rugby Union (RU), yet no study has ...
P. R. Brustio +11 more
doaj +1 more source
A Promising New Approach to Eliminating Selection Bias [PDF]
Laura R. Peck +2 more
openalex +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating and quantifying selection bias in research using placental pathology samples
Introduction Increasing research interest has focused on placental pathology and pregnancy outcomes. Placental pathology examinations that are requested by the delivering provider are often used for research due to convenience, potentially introducing ...
Renee Odom‐Konja +6 more
doaj +1 more source

