Results 61 to 70 of about 4,138,321 (252)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Criteria for the selection of ERP software [PDF]

open access: yes
The implementation of an ERP software package is an important investment for an organization, which is characterized also by a high degree of risk. Selecting the most appropriate software is a necessary condition for a successful implementation.
Adina UTA   +2 more
core  

Other title: Title from HTML header (viewed Nov. 9, 2011): Judicial Selection Commission

open access: yes, 2011
Updated irregularly; Began in 2002?; Title from main search screen (publisher's Web site, viewed Nov. 9, 2011).; At head of title: State of Connecticut.; Harvested from the web on 11/10/11Official website of the Connecticut Judicial Selection Commission.

core   +1 more source

Stochastic Portfolio Selection Problem with Reliability Criteria

open access: yesDiscrete Dynamics in Nature and Society, 2016
Portfolio selection focuses on allocating the capital to a set of securities such that the profit or the risks can be optimized. Due to the uncertainty of the real-world life, the return parameters always take uncertain information in the realistic ...
Xiangsong Meng, Lixing Yang
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Empirical Information Criteria for Time Series Forecasting Model Selection [PDF]

open access: yes
In this paper, we propose a new Empirical Information Criterion (EIC) for model selection which penalizes the likelihood of the data by a function of the number of parameters in the model.
R.J. Hyndman, Md B. Billah, A.B. Koehler
core  

L’inventaire des objets mobiliers religieux des XIXe et XXe siècles : méthodologie

open access: yesIn Situ, 2012
The religious furnishings and artefacts of the 19th century are studied in France in course of the topographical inquiries carried out by the general inventory services in the regions.
Laurence de Finance
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Other title: Title from HTML header (viewed Nov. 9, 2011): Judicial Selection Commission

open access: yes, 2017
Updated irregularly; Began in 2002?; Title from main search screen (publisher's Web site, viewed Nov. 9, 2011).; At head of title: State of Connecticut.; Harvested from the web on 5/8/17Official website of the Connecticut Judicial Selection Commission ...

core   +1 more source

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