Results 91 to 100 of about 1,311,332 (340)
An investigation of genetic algorithm-based feature selection techniques applied to keystroke dynamics biometrics [PDF]
, 2019 Due to the continuous use of social networks, users can be vulnerable to online situations such as paedophilia treats. One of the ways to do the investigation of an alleged pedophile is to verify the legitimacy of the genre that it claims. One possible
Da Costa Abreu, Marjory +3 more
core
Plant Methods, 2018 Charcoal rot is a fungal disease that thrives in warm dry conditions and affects the yield of soybeans and other important agronomic crops worldwide.
Koushik Nagasubramanian +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
A genetic algorithm for the partial binary constraint satisfaction problem: an application to a frequency assignment problem [PDF]
We describe a genetic algorithm for the partial constraint satisfaction problem. The typical elements of a genetic algorithm, selection, mutation and cross-over, are filled in with combinatorial ideas.
Kolen, Antoon
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
An Interference Links Selection Method Based on Genetic Algorithm
Dianxin kexue, 2015 Focusing on interference alignment with partial interference links in multi-cell multiple input multiple output （MIMO）networks, an interference links selection scheme was proposed based on genetic algorithm.
Juan Meng +4 more
doaj +2 more sources
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
A comparative study of the Lasso-type and heuristic model selection methods [PDF]
This study presents a first comparative analysis of Lasso-type (Lasso, adaptive Lasso, elastic net) and heuristic subset selection methods. Although the Lasso has shown success in many situations, it has some limitations.
Ivan Savin
core
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source