Results 81 to 90 of about 1,398,187 (332)

Hybrid genetic algorithm for dual selection [PDF]

open access: yesPattern Analysis and Applications, 2007
Ce travail présente un algorithme génétique hybride pour résoudre le problème suivant : sélectionner dans une base d'exemples le sous ensemble qui présente la meilleure performance en classification avec le plus petit nombre d'attributs pour le plus grand nombre d'exemples.
Ros, F.   +3 more
openaire   +3 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Ship Type Selection and Cost Optimization of Marine Container Ships Based on Genetic Algorithm

open access: yesApplied Sciences
In the context of the deep-sea transportation supply chain, this paper addresses the complex decision-making problem of vessel allocation and carbon emission optimization for container shipping routes.
Ping Xiao, Haiyan Wang
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Tag SNP selection via a genetic algorithm

open access: yesJournal of Biomedical Informatics, 2010
Single Nucleotide Polymorphisms (SNPs) provide valuable information on human evolutionary history and may lead us to identify genetic variants responsible for human complex diseases. Unfortunately, molecular haplotyping methods are costly, laborious, and time consuming; therefore, algorithms for constructing full haplotype patterns from small available
Mahdevar, Ghasem   +4 more
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Feature Selection of Post-Graduation Income of College Students in the United States

open access: yes, 2018
This study investigated the most important attributes of the 6-year post-graduation income of college graduates who used financial aid during their time at college in the United States.
C Avery   +11 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Optimization of Combat Resource Allocation Based on Restricted Tournament Selection Social Genetic Algorithm

open access: yesInternational Journal of Computational Intelligence Systems
To tackle the challenge of combat resource allocation problem (CRAP), especially under resource constraints, the dilemma between the efficiency of combat resource utilization and the efficiency of problem-solving.
Shandong Yuan   +4 more
doaj   +1 more source

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