Results 61 to 70 of about 242,339 (312)

Optimizing Microsatellite Marker Panels for Genetic Diversity and Population Genetic Studies: An Ant Colony Algorithm Approach with Polymorphic Information Content

open access: yesBiology, 2023
Microsatellites are polymorphic and cost-effective. Optimizing reduced microsatellite panels using heuristic algorithms eases budget constraints in genetic diversity and population genetic assessments.
Ryan Rasoarahona   +13 more
doaj   +1 more source

Distributed Genetic Algorithm for Feature Selection

open access: yesCoRR
We empirically show that process-based Parallelism speeds up the Genetic Algorithm (GA) for Feature Selection (FS) 2x to 25x, while additionally increasing the Machine Learning (ML) model performance on metrics such as F1-score, Accuracy, and Receiver Operating Characteristic Area Under the Curve (ROC-AUC).
Michael Potter   +3 more
openaire   +2 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Warehouse location optimization in fresh cold chain logistics based on PSO-GA

open access: yesInternational Journal for Simulation and Multidisciplinary Design Optimization
This study focuses on the site selection problem of fresh cold chain logistics warehouses, using a site selection model to minimize operating costs, improve distribution efficiency, and meet customer needs.
Guo Lina, Wei Yi
doaj   +1 more source

Modelling of a Roulette Wheel Selection Operator in Genetic Algorithms Using Generalized Nets [PDF]

open access: yesBioautomation, 2009
The apparatus of Generalized Nets (GN) is applied here to a description of a selection operator, which is one of the basic genetic algorithm operators. The GN model presented here describes roulette wheel selection.
Pencheva T., Atanassov K., Shannon A.
doaj  

Feature Selection for Image Retrieval based on Genetic Algorithm

open access: yesInternational Journal of Interactive Multimedia and Artificial Intelligence, 2016
This paper describes the development and implementation of feature selection for content based image retrieval. We are working on CBIR system with new efficient technique. In this system, we use multi feature extraction such as colour, texture and shape.
Rashmi R. Welekar, Preeti Kushwaha
doaj   +1 more source

An efficient methodology for discovering both of gene-environment interactions and gene-gene interactions causing genetic diseases

open access: yesEgyptian Informatics Journal, 2020
Genetic diseases are one of the most critical diseases facing human societies, their risk lies in the transmission of genetic characteristics from one generation to another, where the imbalance of these characteristics leads to an unhealthy offspring ...
Mohamed A. El-Rashidy
doaj   +1 more source

Feature selection for modular GA-based classification

open access: yes, 2004
Genetic algorithms (GAs) have been used as conventional methods for classifiers to adaptively evolve solutions for classification problems. Feature selection plays an important role in finding relevant features in classification.
Guan, SU, Zhu, F, Zhu, F., Guan, S.
core   +1 more source

'Enhanced Direct and Indirect Genetic Algorithm Approaches for a Mall Layout and Tenant Selection Problem' [PDF]

open access: yes, 2002
During our earlier research, it was recognised that in order to be successful with an indirect genetic algorithm approach using a decoder, the decoder has to strike a balance between being an optimiser in its own right and finding feasible solutions ...
Aickelin, Uwe   +6 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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