Results 51 to 60 of about 228,099 (265)
Analysis of selection noise in genetic algorithms
Soft ComputingAbstract Selection is often considered as a fundamental force in the evolutionary process. Genetic drift, or selection noise, is an important characteristic of selection methods. It has a direct effect on the performance of genetic algorithms. In this paper, a brief review of methods to analyze genetic drift is given, and known estimations of
Nataliya M. Gulayeva +2 more
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Feature Selection for Image Retrieval based on Genetic Algorithm
International Journal of Interactive Multimedia and Artificial Intelligence, 2016 This paper describes the development and implementation of feature selection for content based image retrieval. We are working on CBIR system with new efficient technique. In this system, we use multi feature extraction such as colour, texture and shape.
Rashmi R. Welekar, Preeti Kushwaha
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Ship Type Selection and Cost Optimization of Marine Container Ships Based on Genetic Algorithm
Applied SciencesIn the context of the deep-sea transportation supply chain, this paper addresses the complex decision-making problem of vessel allocation and carbon emission optimization for container shipping routes.
Ping Xiao, Haiyan Wang
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Genetic Algorithm Based Feature Selection Technique for Electroencephalography Data
Applied Computer Systems, 2019 High dimensionality is a well-known problem that has a huge number of highlights in the data, yet none is helpful for a particular data mining task undertaking, for example, classification and grouping. Therefore, selection of features is used frequently
Ali Tariq +2 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
An improved genetic algorithm for optimizing ensemble empirical mode decomposition method
Systems Science & Control Engineering, 2019 This paper proposes an improved ensemble empirical mode decomposition method based on genetic algorithm to solve the mode mixing problem in empirical mode decomposition (EMD) algorithm as well as the parameters selection issue in ensemble empirical mode ...
Dabin Zhang +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source