Results 51 to 60 of about 6,256,599 (289)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Self-Tune Linear Adaptive-Genetic Algorithm for Feature Selection

IEEE Access, 2019
Genetic algorithm (GA) is an established machine learning technique used for heuristic optimisation purposes. However, this natural selection-based technique is prone to premature convergence, especially of the local optimum event.
Ching Sheng Ooi, Meng Hee Lim, Mohd Salman Leong   +2 more
doaj   +1 more source

Protection Strategy Selection Model Based on Genetic Ant Colony Optimization Algorithm

Mathematics, 2022
Industrial control systems (ICS) are facing an increasing number of sophisticated and damaging multi-step attacks. The complexity of multi-step attacks makes it difficult for security protection personnel to effectively determine the target attack path ...
Xinzhan Li, Yang Zhou, Xin Li, Lijuan Xu, Dawei Zhao   +4 more
doaj   +1 more source

Distributed Genetic Algorithm for Feature Selection

CoRR
We empirically show that process-based Parallelism speeds up the Genetic Algorithm (GA) for Feature Selection (FS) 2x to 25x, while additionally increasing the Machine Learning (ML) model performance on metrics such as F1-score, Accuracy, and Receiver Operating Characteristic Area Under the Curve (ROC-AUC).
Michael Potter, Ayberk Yarkin Yildiz, Nishanth Marer Prabhu, Cameron Gordon   +3 more
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Multi-user indoor optical wireless communication system channel control using a genetic algorithm [PDF]

, 2011
A genetic algorithm controlled multispot transmitter is demonstrated that is capable of optimising the received power distribution for randomly aligned single element receivers in multiple fully diffuse optical wireless communications systems with ...
M.S. Leeson, R.J. Green, E.L. Hines, Leeson, Mark S., Hines, Evor, Higgins, Matthew D., Green, Roger, M.D. Higgins   +7 more
core   +1 more source

Warehouse location optimization in fresh cold chain logistics based on PSO-GA

International Journal for Simulation and Multidisciplinary Design Optimization
This study focuses on the site selection problem of fresh cold chain logistics warehouses, using a site selection model to minimize operating costs, improve distribution efficiency, and meet customer needs.
Guo Lina, Wei Yi
doaj   +1 more source

Genetic Algorithm Based Feature Selection Technique for Electroencephalography Data

Applied Computer Systems, 2019
High dimensionality is a well-known problem that has a huge number of highlights in the data, yet none is helpful for a particular data mining task undertaking, for example, classification and grouping. Therefore, selection of features is used frequently
Ali Tariq, Nawaz Asif, Sadia Hafiza Ayesha   +2 more
doaj   +1 more source

An efficient methodology for discovering both of gene-environment interactions and gene-gene interactions causing genetic diseases

Egyptian Informatics Journal, 2020
Genetic diseases are one of the most critical diseases facing human societies, their risk lies in the transmission of genetic characteristics from one generation to another, where the imbalance of these characteristics leads to an unhealthy offspring ...
Mohamed A. El-Rashidy
doaj   +1 more source