Results 31 to 40 of about 6,256,599 (289)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

SLA based cloud service composition using genetic algorithm [PDF]

open access: yes, 2016
Cloud computing tends to provide high quality on-demand services to the users. Numerous services are evolving today. Functionally similar services are having different non-functional properties such as reliability, availability, accessibility, response ...
N Sasikaladevi, Sasikaladevi, N
core   +1 more source

Evolutionary Schema of Modeling Based on Genetic Algorithms

open access: yesStudies in Logic, Grammar and Rhetoric, 2015
In this paper, I propose a populational schema of modeling that consists of: (a) a linear AFSV schema (with four basic stages of abstraction, formalization, simplification, and verification), and (b) a higher-level schema employing the genetic algorithm (
Stacewicz Paweł
doaj   +1 more source

A Selection Process for Genetic Algorithm Using Clustering Analysis

open access: yesAlgorithms, 2017
This article presents a newly proposed selection process for genetic algorithms on a class of unconstrained optimization problems. The k-means genetic algorithm selection process (KGA) is composed of four essential stages: clustering, membership phase ...
Adam Chehouri   +4 more
doaj   +1 more source

Two-stage hybrid genetic algorithm for robot cloud service selection

open access: yesJournal of Cloud Computing: Advances, Systems and Applications, 2023
Robot cloud service platform is a combination of cloud computing and robotics, providing intelligent cloud services for many robots. However, to select a cloud service that satisfys the robot’s requirements from the massive services with different QoS ...
Lei Yin   +5 more
doaj   +1 more source

Boosting Genetic Algorithms with Self-Adaptive Selection [PDF]

open access: yes2006 IEEE International Conference on Evolutionary Computation, 2006
In this paper we evaluate a new approach to selection in genetic algorithms (GAs). The basis of our approach is that the selection pressure is not a superimposed parameter defined by the user or some Boltzmann mechanism. Rather, it is an aggregated parameter that is determined collectively by the individuals in the population. We implement this idea in
Eiben, A.E., Schut, M.C., de Wilde, A.R.
openaire   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

A new genetic algorithm for multi-label correlation-based feature selection. [PDF]

open access: yes, 2015
This paper proposes a new Genetic Algorithm for Multi-Label Correlation-Based Feature Selection (GA-ML-CFS). This GA performs a global search in the space of candidate feature subset, in order to select a high-quality feature subset is used by a multi ...
Jungjit, Suwimol, Freitas, Alex A.
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

GCMD: Genetic Correlation Multi-Domain Virtual Network Embedding Algorithm

open access: yesIEEE Access, 2021
With the increase of network scale and the complexity of network structure, the problems of traditional Internet have emerged. At the same time, the appearance of network function virtualization (NFV) and network virtualization technologies has largely ...
Peiying Zhang   +5 more
doaj   +1 more source

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