Results 41 to 50 of about 6,256,599 (289)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Modified Floating Search Feature Selection Based on Genetic Algorithm
MATEC Web of Conferences, 2018 Classification performance is adversely impacted by noisy data .Selecting features relevant to the problem is thus a critical step in classification and difficult to achieve accurate solution, especially when applied to a large data set. In this article,
Homsapaya Kanyanut, Sornil Ohm
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Parameter Selection in Genetic Algorithms
Journal of Systemics, Cybernetics and Informatics, 2004 In this study, we provide a new taxonomy of parameters of genetic algorithms (GA), structural and numerical parameters, and analyze the effect of numerical parameters on the performance of GA based simulation optimization applications with experimental design techniques. Appropriate levels of each parameter are proposed for a particular problem domain.
BOYABATLI, Onur, SABUNCUOGLU, Ihsan
openaire +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
A self-organizing random immigrants genetic algorithm for dynamic optimization problems [PDF]
, 2007 This is the post-print version of the article. The official published version can be obtained from the link below - Copyright @ 2007 SpringerIn this paper a genetic algorithm is proposed where the worst individual and individuals with indices close to ...
Yang, S +7 more
core +1 more source
FastTree-Guided Genetic Algorithm for Credit Scoring Feature Selection
ComputersFeature selection is pivotal in enhancing the efficiency of credit scoring predictions, where misclassifications are critical because they can result in financial losses for lenders and exclusion of eligible borrowers. While traditional feature selection
Rashed Bahlool +2 more
doaj +1 more source
Compare Between Genetic Algorithm and Clonal Selection Algorithm To Pattern Recognition Latin's Numbers [PDF]
مجلة التربية والعلم, 1970 This work involves the use some of Artificial intelligence techniques algorithms which are genetic algorithm and artificial immune system algorithm- clonal selection algorithm.
Maha Mohammed
doaj +1 more source
Research On Energy-saving Operation Of High-speed Trains Based On Improved Genetic Algorithm
Journal of Applied Science and Engineering, 2022 The traditional genetic algorithm has been widely used in energy-saving optimization of train operation, but due to the uncertainty of the evolution direction of it’s population chromosomes, it has caused some problems such as a large amount of local ...
Hongxia Niu, Tao Hou, Yu Chen
doaj +1 more source
Parallelization of Genetic Algorithm with Sexual Selection
IEEJ Transactions on Electronics, Information and Systems, 2003 AbstractWe propose a parallel genetic algorithm with sexual selection. In genetic algorithms with sexual selection with one population, females keep their traits around local optima by using a lower mutation rate than that of the males, while the males change their traits actively.
Omori, Kiyohiro +3 more
openaire +2 more sources