Results 101 to 110 of about 436,618 (310)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

LEARNING MATERIALS SELECTION FOR DIFFERENTIATED INSTRUCTION OF ENGLISH FOR SPECIFIC PURPOSES OF FUTURE PROFESSIONALS IN THE FIELD OF INFORMATION TECHNOLOGY

open access: yesНаукові записки Тернопільського національного педагогічного університету імені Володимира Гнатюка. Серія: Педагогіка, 2017
In conditions of differentiation the learning materials selection will optimize the training English for Specific Purposes of the future professionals in the field of information technology at university level. The purpose of the article is to define the
Oksana Synekop
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Beyond the microscope: integrating inclusion, diversity, equity, and accessibility principles in immunology education through the IDE-A rubric

open access: yesFrontiers in Education
Textbooks are essential resources for developing immunological literacy. This article emphasizes expanding educational focus beyond traditional technical content to more broadly encompass inclusion and equity in the classroom.
Claudette P. Davis   +5 more
doaj   +1 more source

Non-random mating for selection with restricted rates of inbreeding and overlapping generations [PDF]

open access: yes, 2002
Minimum coancestry mating with a maximum of one offspring per mating pair (MC1) is compared with random mating schemes for populations with overlapping generations. Optimum contribution selection is used, whereby ΔF is restricted.
Anna K Sonesson   +9 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

A note on convergence in measure and selection principles [PDF]

open access: yes, 2012
It is proved that some classes of sequences of measurable functions satisfy certain selection principles related to special modes of convergence (convergence in measure, almost everywhere convergence, almost uniform convergence, mean convergence ...
Đurčić, Dragan   +3 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

PRINCIPLES OF ANIMAL BREEDING [PDF]

open access: yesPoljoprivreda, 2014
University textbook Principles of Animal Breeding is intended for students of agriculture and veterinary medicine. The material is the adapted curricula of undergraduate and graduate level studies in the framework of which the modules Principles of ...
Sonja Jovanovac
doaj  

Optimization of Methods for the Selection of Multifocal Intraocular Correction in Eye-Lens Surgery

open access: yesOftalʹmologiâ, 2019
Purpose: to develop a methodology for the selection of patients for multifocal intraocular correction with an individual definition of the IOL type based on the data obtained from a preoperative questionnaire and a trial selection of multifocal contact ...
N. E. Temirov   +2 more
doaj   +1 more source

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