Results 81 to 90 of about 4,706,170 (209)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Beyond the microscope: integrating inclusion, diversity, equity, and accessibility principles in immunology education through the IDE-A rubric

Frontiers in Education
Textbooks are essential resources for developing immunological literacy. This article emphasizes expanding educational focus beyond traditional technical content to more broadly encompass inclusion and equity in the classroom.
Claudette P. Davis, Erika Lorenzana Del Villar, Sumali Pandey, Ekaterini Papadopoulou, Zemirah Ngow, Cynthia A. Wenner   +5 more
doaj   +1 more source

Note on selection principles of Kocinac

, 2012
This paper investigates α d , i ∈ {2,3,4}, selection principles (which are modification of known selection principles of Koy cinac) on a double sequence of double sequences of real numbers which converge to a point a ∈ R in Pringsheim's sense. A stronger
D. Djurcic, M. Žižović, A. Petojević
semanticscholar   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Optimization of Methods for the Selection of Multifocal Intraocular Correction in Eye-Lens Surgery

Oftalʹmologiâ, 2019
Purpose: to develop a methodology for the selection of patients for multifocal intraocular correction with an individual definition of the IOL type based on the data obtained from a preoperative questionnaire and a trial selection of multifocal contact ...
N. E. Temirov, N. N. Temirov, G. A. Klimenova   +2 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

LEARNING MATERIALS SELECTION FOR DIFFERENTIATED INSTRUCTION OF ENGLISH FOR SPECIFIC PURPOSES OF FUTURE PROFESSIONALS IN THE FIELD OF INFORMATION TECHNOLOGY

Наукові записки Тернопільського національного педагогічного університету імені Володимира Гнатюка. Серія: Педагогіка, 2017
In conditions of differentiation the learning materials selection will optimize the training English for Specific Purposes of the future professionals in the field of information technology at university level. The purpose of the article is to define the
Oksana Synekop
doaj   +1 more source

Biological Principles and Threshold Concepts for Understanding Natural Selection

, 2017
Modern evolutionary theory is both a central theory and an integrative framework of the life sciences. This is reflected in the common references to evolution in modern science education curricula and contexts.
L. Tibell, U. Harms
semanticscholar   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Thematic proto-roles and argument selection

, 1991
As a novel attack on the perennially vexing questions of the theoretical status of thematic roles and the inventory of possible roles, this paper defends a strategy of basing accounts of roles on more unified domains of linguistic data than have been ...
David R. Dowty
semanticscholar   +1 more source