Results 71 to 80 of about 4,706,170 (209)

Aligning preclinical AML models with immunotherapy development: principles for model selection

open access: yesFrontiers in Immunology
Advances in immunotherapy for acute myeloid leukemia (AML) have revealed critical gaps in selection of appropriate preclinical models. Conventional cytotoxic and targeted therapies could be tested in relatively straightforward systems.
Efe Karaca   +5 more
doaj   +1 more source

Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression

open access: yesAIP Advances, 2012
Empirical studies give increased support for the hypothesis that the sporadic form of cancer is an age-related metabolic disease characterized by: (a) metabolic dysregulation with random abnormalities in mitochondrial DNA, and (b) metabolic alteration ...
Paul Davies   +2 more
doaj   +1 more source

SELECTION OF MAJOR WAYS IMAGE AND PRINCIPLES REGISTRATION CARD ENVIRONMENTAL AND CONSERVATION

open access: yesInterCarto. InterGIS, 2015
The basic principles of developing and design of environmental maps and maps of environmental protection of the Republic of Uzbekistan are considered.
J. S. Karabaev
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Principles of Selection, Implementation and Utilization of RFID in Supply Chain Management

open access: yesPromet (Zagreb), 2009
The paper deals with RFID (Radio Frequency Identification)implementation and utilization within supply chain managementand also includes the economic feasibility of rollingout RFID.
Juraj Vaculik   +2 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Ethnography : Principles in Practice

open access: yes, 1983
Features include the selection and sampling of cases, the problems of access, observation and interviewing, recording and filing data, and the process of data analysis.
M. Hammersley, P. Atkinson
semanticscholar   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Design Preferences and Consumer's Selection Principles

open access: yes, 2012
This study describes research into Malaysian household furniture. The principal purpose of this study was to explore the design criteria employed by designers, design managers, professionals and the selection principles used by urban consumers residing ...
M. Awang   +2 more
semanticscholar   +1 more source

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