Results 71 to 80 of about 4,706,170 (209)
Aligning preclinical AML models with immunotherapy development: principles for model selection
Advances in immunotherapy for acute myeloid leukemia (AML) have revealed critical gaps in selection of appropriate preclinical models. Conventional cytotoxic and targeted therapies could be tested in relatively straightforward systems.
Efe Karaca +5 more
doaj +1 more source
Empirical studies give increased support for the hypothesis that the sporadic form of cancer is an age-related metabolic disease characterized by: (a) metabolic dysregulation with random abnormalities in mitochondrial DNA, and (b) metabolic alteration ...
Paul Davies +2 more
doaj +1 more source
SELECTION OF MAJOR WAYS IMAGE AND PRINCIPLES REGISTRATION CARD ENVIRONMENTAL AND CONSERVATION
The basic principles of developing and design of environmental maps and maps of environmental protection of the Republic of Uzbekistan are considered.
J. S. Karabaev
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Principles of Selection, Implementation and Utilization of RFID in Supply Chain Management
The paper deals with RFID (Radio Frequency Identification)implementation and utilization within supply chain managementand also includes the economic feasibility of rollingout RFID.
Juraj Vaculik +2 more
doaj +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Ethnography : Principles in Practice
Features include the selection and sampling of cases, the problems of access, observation and interviewing, recording and filing data, and the process of data analysis.
M. Hammersley, P. Atkinson
semanticscholar +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Design Preferences and Consumer's Selection Principles
This study describes research into Malaysian household furniture. The principal purpose of this study was to explore the design criteria employed by designers, design managers, professionals and the selection principles used by urban consumers residing ...
M. Awang +2 more
semanticscholar +1 more source

