Results 131 to 140 of about 436,618 (310)
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Approximate model and clonal selection algorithm based optimization of heating channels for variotherm injection mold [PDF]
The integration of an approximate model and a clonal selection algorithm (CSA) is considered to one of the most effective ways to solve complex optimization design problems in engineering.
Xiping Li, Ningning Gong, Tingwei Ji
doaj
Evolutionary multiobjective optimization with hybrid selection principles
Achieving balance between convergence and diversity is a basic issue in evolutionary multiobjective optimization (EMO). In this paper, we propose a hybrid EMO algorithm that assigns different selection principles to two separate and co-evolving archives.
Kalyanmoy Deb +5 more
core +1 more source
Abstract A selection principle that permits only the observed combinations of quarks to exist as well-separated clusters, is formulated in terms of a boundary condition on the many-particle wave function. Calculated quantities are in reasonable agreement with experiment.
openaire +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
APPLYING SUSTAINABILITY PRINCIPLES IN THE SELECTION OF BUILDING MATERIALS FOR BUILDINGS CONSTRUCTION
The research's main object was to determine factors that affect the selection of building materials according to sustainability principles. The research objective was achieved through two stages; the first stage included a theoretical study about ...
Entisar K. Al-Geelawee +1 more
doaj
The advancement of the information era has raised growing interest in triboelectric nanogenerators (TENGs) as environmentally friendly micropower sources.
Muhammad Naeem Shah +10 more
doaj +1 more source
Products and selection principles
10 ...
Babinkostova, Liljana, Scheepers, Marion
openaire +2 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source

