Results 131 to 140 of about 436,618 (310)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Approximate model and clonal selection algorithm based optimization of heating channels for variotherm injection mold [PDF]

open access: yesInternational Journal of Advanced Design and Manufacturing Technology, 2013
The integration of an approximate model and a clonal selection algorithm (CSA) is considered to one of the most effective ways to solve complex optimization design problems in engineering.
Xiping Li, Ningning Gong, Tingwei Ji
doaj  

Evolutionary multiobjective optimization with hybrid selection principles

open access: yes, 2015
Achieving balance between convergence and diversity is a basic issue in evolutionary multiobjective optimization (EMO). In this paper, we propose a hybrid EMO algorithm that assigns different selection principles to two separate and co-evolving archives.
Kalyanmoy Deb   +5 more
core   +1 more source

Quark selection principle

open access: yesPhysics Letters B, 1970
Abstract A selection principle that permits only the observed combinations of quarks to exist as well-separated clusters, is formulated in terms of a boundary condition on the many-particle wave function. Calculated quantities are in reasonable agreement with experiment.
openaire   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

APPLYING SUSTAINABILITY PRINCIPLES IN THE SELECTION OF BUILDING MATERIALS FOR BUILDINGS CONSTRUCTION

open access: yesJournal of Engineering and Sustainable Development, 2016
The research's main object was to determine factors that affect the selection of building materials according to sustainability principles. The research objective was achieved through two stages; the first stage included a theoretical study about ...
Entisar K. Al-Geelawee   +1 more
doaj  

First Principles Calculation Guided Material Selection of Poly(propylenemonothiocarbonate) for High-Performance Triboelectric Nanogenerators

open access: yesEnergy Material Advances
The advancement of the information era has raised growing interest in triboelectric nanogenerators (TENGs) as environmentally friendly micropower sources.
Muhammad Naeem Shah   +10 more
doaj   +1 more source

Products and selection principles

open access: yes, 2007
10 ...
Babinkostova, Liljana, Scheepers, Marion
openaire   +2 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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