Results 111 to 120 of about 3,596,398 (274)

Bioindicators selection in the strategies for monitoring microplastic pollution

Ecological Indicators
Micro(nano)plastics (MNPs) are pervasive pollutants posing significant environmental and health risks. Selecting appropriate sentinel species to assess MNPs in terrestrial and aquatic environments involves considering factors such as species behavior ...
Paolo Pastorino, Damià Barceló
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Enhancing reading strategies through literature selection in EFL classrooms

Indonesian Journal of Education and Pedagogy
This study presents a detailed examination of how to enhance reading strategies with selected literary genres using the library research method. In addition to library resources, the information collection process has been monitored through various ...
Ayşegül Durak, Fatih Yavuz
doaj   +1 more source

Admissible strategies in semimartingale portfolio selection [PDF]

The choice of admissible trading strategies in mathematical modelling of financial markets is a delicate issue, going back to Harrison and Kreps [HK79].
Ales Cerny, Sara Biagini
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

External stakeholder risk response strategies selection in project portfolio

Heliyon
To improve the effectiveness of external stakeholder risks (ESRs) management in project portfolios (PPs), a portfolio-wide risk response approach is required.
Libiao Bai, Shuyun Kang, Fang Li, Ziwen Zhang, Jiayu Li, Xixi Luo   +5 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Robust Access Points Selection Strategies for Dynamic Indoor Localization

IEEE Access
The proliferation of mobile devices has fueled the demand for indoor location-based services. Consequently, a plethora of techniques have emerged to facilitate object and device localization in indoor environments.
Aqilah Binti Mazlan, Yin Hoe Ng
doaj   +1 more source

Investment Fund Portfolio Selection Strategy

Verslas: teorija ir praktika, 2007
The paper is based on the proceedings of the International Conference ‘Business and Management 2006’. The problems of investment fund portfolio selection are discussed further and deeper, though the problem solved differs by covered period, selected stocks, and the principles of stock selection.
openaire   +4 more sources