Results 141 to 150 of about 11,499,836 (351)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

New Adaptive Selection Strategies for Distributed Adaptive Metaheuristic Selection

open access: yes, 2015
International audienceDistributed Adaptive Metaheuristics Selection (DAMS) is a framework dedicated to adaptive optimization in distributed environments.
Christopher Jankee   +7 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Bioindicators selection in the strategies for monitoring microplastic pollution

open access: yesEcological Indicators
Micro(nano)plastics (MNPs) are pervasive pollutants posing significant environmental and health risks. Selecting appropriate sentinel species to assess MNPs in terrestrial and aquatic environments involves considering factors such as species behavior ...
Paolo Pastorino, Damià Barceló
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Selection of surgical strategies for vulvar Paget's disease

open access: yesChinese Medical Journal, 2021
Yu Liu   +6 more
doaj   +1 more source

Enhancing reading strategies through literature selection in EFL classrooms

open access: yesIndonesian Journal of Education and Pedagogy
This study presents a detailed examination of how to enhance reading strategies with selected literary genres using the library research method. In addition to library resources, the information collection process has been monitored through various ...
Ayşegül Durak, Fatih Yavuz
doaj   +1 more source

A REGIONAL COMPARISON OF RISK-EFFICIENT SOYBEAN MARKETING STRATEGIES

open access: yes
Risk-efficient portfolios from a subset of marketing strategies were identified using Target-MOTAD. Portfolios were generated for Illinois, Arkansas, and South Carolina to determine whether regional price and yield characteristics affected the optimal ...
Curtis, Charles E., Jr.   +2 more
core  

Vendor selection and evaluation : an activity based costing appoach. [PDF]

open access: yes
In this paper we propose an Activity Based Costing approach for vendor selection and evaluation. This system allows us to compute total costs caused by a supplier in a firm's production process, thereby increasing the objectivity in the selection process.
Konings, Joep, Roodhooft, Filip
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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