Meningeal Lymphatic LTBR Deficiency Links Spinal Cord Injury to Secondary Brain Pathology
Spinal cord injury (SCI) induces remote brain alterations beyond the injured spinal cord. This study links dysfunction of meningeal lymphatic vessels (mLVs) to neuroinflammation and neuronal injury after SCI. LTBR‐mediated lymphatic restoration improves meningeal lymphatic integrity and neurological outcomes, highlighting LTBR as a potential regulator ...
Yi Chen +12 more
wiley +1 more source
Stereogenic and Conformational Diversity in Multicomponent Ir-Catalyzed Borylation of Arenes: Unveiling the Origin of Enantioselectivity by Conformational Sampling. [PDF]
Wang JS, You XX, Li L, Su ZM, Zhong RL.
europepmc +1 more source
This study established a one‐step method inducing pro‐spermatogonia‐like (activating SOX17) and oogonia‐like (activating SOX17/TFAP2C) cells from porcine pgEpiSCs with a NANOS3‐tdTomato reporter. EGF activates the core PGC program and supports survival; BMP4 further induces NANOS3 and DDX4 expression; IWR1 enhances PGCLC efficiency by suppressing ...
Pengcheng He +14 more
wiley +1 more source
Unveiling the thermodynamic-kinetic trade-off effect on acid sites in zeolite-catalyzed alcohol dehydration. [PDF]
Hu M +6 more
europepmc +1 more source
A self‐sustainable vehicular vibration and indoor environment monitoring IoT platform is developed which integrates a hybrid spring‐coupled broadband energy harvester with a machine learning‐assisted PAN‐CuSCN nanofiber triboelectric vibration sensor for subtle‐to‐wide‐range vibration detection and road/speed classification.
Trilochan Bhatta +6 more
wiley +1 more source
Unlocking efficient electrocatalytic removal of trace emerging contaminants via synchronized pollutant enrichment and electron delivery. [PDF]
Pan Y +10 more
europepmc +1 more source
Chiral‐Nematic Lattice Instability in Charge Density Wave of 1T‐TiSe2
The charge density wave of 1T‐TiSe2 appears chiral to surface probes yet loses all symmetry in spectroscopic measurements. This study reveals how cooperative condensation of multiple phonon modes stabilizes a chiral monoclinic ground state, while a shallow nematic energy landscape allows the lattice to break the remaining symmetry at negligible cost ...
Abdurrafi Ahsan Alghifari +3 more
wiley +1 more source
Unsymmetrical Diaryl Borinium Cation: From Solvent-Dependent Radical Behavior to an Elusive Chloroborinium Intermediate. [PDF]
Chen BA +5 more
europepmc +1 more source
HADHA K406 lactylation fuels fatty acid β‐oxidation and HMGCR‐dependent cholesterol biosynthesis, fostering immunosuppressive MDSCs and exhausted CD8+ T cells in gastric cancer. Loss of this modification blocks cholesterol production, remodels the tumor microenvironment, and tumor growth is suppressed via combined inhibition of HMGCR and LDHA ...
Maoxiao Feng +10 more
wiley +1 more source
Gas Vesicles and Acoustic Protein Nanostructures in Molecular Ultrasound Nanomedicine: Translational Archetypes, Biomaterial Design, and Barriers to Clinical Realization. [PDF]
Cui A, Du Y, Sun L.
europepmc +1 more source

