Results 31 to 40 of about 552 (238)

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

RDA-ANN Based Real-Time Selective Harmonic Elimination in Multilevel Inverter Fed by PV Panels

Energies
This work presents a novel method known as the Red Deer Algorithm-Based Artificial Neural Network (RDA-ANN) for managing real-time voltage and harmonic control in a cascade H-bridge multilevel inverter (CHB-MLI) that is fed by photovoltaic (PV) panels ...
Hulusi Karaca, Mehmet Akif Şahman, Yasin Bektaş   +2 more
doaj   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan, Praveen Velammal, Kanmani Muthiah, Madhu Jatty, Christopher Adams   +4 more
wiley   +1 more source

A new low cost cascaded transformer multilevel inverter topology using minimum number of components with modified selective harmonic elimination modulation

Ain Shams Engineering Journal, 2015
In this paper, a novel cascaded transformer multilevel inverter is proposed. The number of the switching devices is reduced in the proposed topology. This topology comprises of a DC source, several single phase low-frequency transformers, two main power ...
H. Khounjahan, M.R. Banaei, Amir Farakhor   +2 more
doaj   +1 more source

Non-traditional method-based solution for elimination of lower order harmonics in voltage source inverter feeding an induction motor drive [PDF]

Serbian Journal of Electrical Engineering, 2008
This paper presents an efficient and reliable Genetic Algorithm-based solution for Specific Harmonic Elimination (SHE) switching pattern. This method eliminates considerable amount of lower order line voltage harmonics in Pulse Width Modulation (PWM ...
Vargese Jegathesan, Jovitha Jerome
doaj   +1 more source

Microscale Patterning of Ultrahigh‐Viscosity Metallic‐Polymer Composites via Embedded Droplet Writing

Advanced Functional Materials, EarlyView.
A hybrid additive manufacturing platform integrates direct droplet writing of metallic composite with VAT photopolymerization to fabricate architected soft magnetic composites. This approach enables microscale patterning of high‐viscosity materials for programmable actuators, adaptive fluidic devices, and switchable adhesives, offering tunable ...
Yeowon Yoon, Jian Ni, Sungmo Park, Yang Xu, Yong Chen   +4 more
wiley   +1 more source

The selective harmonic elimination based optimal fundamental frequency modulation for multilevel converter

矿业科学学报, 2017
The selective harmonic elimination(SHE) based staircase modulation is a commonly used fundamental frequency modulation strategy for multilevel converters.However, the solutions to the staircase SHE equations cannot cover the full range of modulation ...
Yang Kehu, Zhang Jianjun, Wang Yubo, Li Xiangyu   +3 more
doaj  

Application of the Newton–Raphson algorithm for enhanced harmonic reduction in seven-level packed U-cell multilevel inverters

Electrical engineering & Electromechanics
Introduction. Recently, multilevel inverters (MLIs) have been widely investigated for industrial and renewable energy systems as they are valuable in applications where they can produce clean, high-fidelity electrical signals that minimize harmonic ...
O. A. Y. Amran, N. A. Windarko, I. Syarif, T. B. J. Gemilang   +3 more
doaj   +1 more source