Results 51 to 60 of about 34,534 (255)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Yttrium-90 Radioembolization as the Major Treatment of Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma, 2023
Chun-Yen Yu,1,* Po-Hsun Huang,1,* Leo Leung-Chit Tsang,1 Hsien-Wen Hsu,1 Wei-Xiong Lim,1 Ching-Chun Weng,1 Tung-Liang Huang,1 Chien-Chin Hsu,2 Chao-Long Chen,3 Hsin-You Ou,1 Yu-Fan Cheng1 1Department of Diagnostic Radiology, Kaohsiung Chang Gung ...
Yu CY, Huang PH, Tsang LLC, Hsu HW, Lim WX, Weng CC, Huang TL, Hsu CC, Chen CL, Ou HY, Cheng YF   +10 more
doaj  

Gram‐Scale Production of Iron Oxide Rubik‐Cube Nanoparticles: New Tools for the Clinical Translation of Magnetic Hyperthermia and Magnetic Particle Imaging

Advanced Functional Materials, EarlyView.
This work reports the first gram‐scale solvothermal synthesis of ‘Rubik's cube’ nanoparticles—cubic, dendritic multicore structures with tuneable sizes and exceptional magnetic heating performance. Featuring iron oxide single‐domain character, with low coercivity fields, high magnetization, and strong MPI signals, they enable viscosity‐independent ...
Giusy M. R. Rizzo, Niccolò Silvestri, Nabila Jarmouni, Helena Gavilán, Hamza Yakubu, Daniel Arenas‐Esteban, Sara Bals, Paola Parlanti, Mauro Gemmi, Ross Clark Prado, Anna Cristina S. Samia, Verónica Salgueiriño, Teresa Pellegrino   +12 more
wiley   +1 more source

Efficacy and safety of selective internal radiation therapy with yttrium-90 for the treatment of unresectable hepatocellular carcinoma

BMC Gastroenterology, 2021
Background This retrospective analysis was undertaken to evaluate the efficiency of SIRT with Y-90 microspheres and determined prognostic factors affecting patients with unresectable HCC. Methods A total of 97 patients diagnosed with unresectable HCC who
Nguyen Van Thai, Nguyen Tien Thinh, Thai Doan Ky, Mai Hong Bang, Dinh Truong Giang, Le Ngoc Ha, Mai Hong Son, Dao Duc Tien, Hyun Woong Lee   +8 more
doaj   +1 more source

Selective internal radiation therapy for liver metastases from colorectal cancer

Cochrane Database of Systematic Reviews, 2008
Liver metastases are often the dominant site of metastatic disease in colorectal cancer. Selective internal radiation therapy (SIRT) involves embolising radiolabeled spheres (SIR-Spheres) into the arterial supply of the liver with the aim of improving the control of liver metastases.To assess the effectiveness and toxicity of SIRT in the treatment of ...
Amanda, Townsend, Timothy, Price, Christos, Karapetis   +2 more
openaire   +3 more sources

Engineering a Sonotherapeutic RBC Membrane‐Derived Nanoparticle Platform for the Treatment of Liver Cancer

Advanced Functional Materials, EarlyView.
Herein, an RBC membrane‐derived nanoparticle (CMN‐ICG) is engineered to efficiently deliver a sonosensitizing agent, indocyanine green (ICG), for sonotherapy of hepatocellular carcinoma (HCC). CMN‐ICG exhibits excellent cytocompatibility, significantly enhances hepatocyte uptake, and produces excessive reactive oxygen species (ROS) upon ultrasound ...
Alap Ali Zahid, Aishik Chakraborty, Wei Luo, Juhi Bora, John Joseph Kelly, John Andrew Ronald, Arghya Paul   +6 more
wiley   +1 more source

Application progress of Yttrium-90 microsphere selective internal radiation therapy on metastatic liver cancer

Zhongguo Linchuang Yixue
Yttrium-90 microsphere selective internal radiation therapy (90Y-SIRT) has been widely used in the treatment of malignant liver cancers, and its safety and efficacy have been fully validated.
Guanxiang ZHUO, Linhe GAN, Jinfeng LIAN, Yilin WANG   +3 more
doaj   +1 more source

Selective internal radiation therapy first-line therapy – SIRFLOX and FOXFIRE

European Journal of Cancer Supplements, 2012
Liver-directed therapies such as selective internal radiation therapy (SIRT, also known as radioembolisation) are investigational treatments that have the potential to improve local control and survival in metastastic colorectal cancer (mCRC) confined to the liver.
openaire   +1 more source

Structural Porosity and Low Mineral Density in Enamel Rods Drive Molar Incisor Hypomineralisation

Advanced Functional Materials, EarlyView.
This study uses advanced imaging modalities on multiple length scales to show that molar‐incisor hypomineralization does not present as a locally homogeneous pathology. Instead, microstructural defects, characterized through non‐mineralized, protein‐rich sheaths and an altered mineral structure in between prism rods, resulting in local differences in ...
Katharina Jähn‐Rickert, Johannes Krug, Gudrun Lotze, Imke A.K. Fiedler, Diana Freund, Ezgi Deniz Türkoğlu, Christine Plumeyer, Felix N. von Brackel, Anton Davydok, Manfred Burghammer, Thomas Beikler, Thomas F. Keller, Katrin Bekes, Elizabeth A. Zimmermann, Björn Busse   +14 more
wiley   +1 more source

Selective internal radiation therapy for other liver metastases

European Journal of Cancer Supplements, 2012
YYttrium-90LivertumoursBreastcancerMelanomaLivermetastasesSelective internal radiation therapy (SIRT), also termedradioembolisation, is a form of brachytherapy that wasdeveloped to improve local control of either primaryor secondary malignancies within the liver. High-dose radiation, delivered via the hepatic artery usingyttrium-90 (
openaire   +1 more source